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Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Inhibition of PLK1 in HEK293T cells assessed as reduction in phosphorylation of TCTP at S46 residue at 30 to 100 nM incubated for 6 hrs by immunoblotting analysis
Assay data:4 Active, 6 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
AlphaLisa Assay from US Patent US11279703: "Fused pyrimidine compounds as BRD4 and JAK2 dual inhibitors and methods for use thereof"
Assay data:219 Active, 4 Activity ≤ 1 nM, 177 Activity ≤ 1 µM, 229 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
in vitro kinase inhibition assay from US Patent US10308662: "Thienopyranones as kinase and epigenetic inhibitors"
Assay data:28 Active, 20 Activity ≤ 1 µM, 28 Tested
NCI human tumor cell line growth inhibition assay. Data for the KM12 Non-Small Cell Lung cell line, single concentration
Assay data:3444 Active, 76734 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Non-Small Cell Lung cell line, single concentration
Assay data:3073 Active, 74254 Tested
NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Non-Small Cell Lung cell line, single concentration
Assay data:5131 Active, 77082 Tested
NCI human tumor cell line growth inhibition assay. Data for the MCF7 Non-Small Cell Lung cell line, single concentration
Assay data:4318 Active, 77515 Tested
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Non-Small Cell Lung cell line, single concentration
Assay data:3653 Active, 76840 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Non-Small Cell Lung cell line, single concentration
Assay data:5608 Active, 76570 Tested
NCI human tumor cell line growth inhibition assay. Data for the BT-549 Non-Small Cell Lung cell line, single concentration
Assay data:2768 Active, 73031 Tested
NCI human tumor cell line growth inhibition assay. Data for the T-47D Non-Small Cell Lung cell line, single concentration
Assay data:3353 Active, 74196 Tested
NCI human tumor cell line growth inhibition assay. Data for the NCI/ADR-RES Non-Small Cell Lung cell line, single concentration
Assay data:3002 Active, 76488 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-231/ATCC Non-Small Cell Lung cell line, single concentration
Assay data:3404 Active, 76205 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-3 Non-Small Cell Lung cell line, single concentration
Assay data:5012 Active, 76370 Tested
NCI human tumor cell line growth inhibition assay. Data for the IGROV1 Non-Small Cell Lung cell line, single concentration
Assay data:3242 Active, 74206 Tested
NCI human tumor cell line growth inhibition assay. Data for the SK-OV-3 Non-Small Cell Lung cell line, single concentration
Assay data:2145 Active, 74774 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-4 Non-Small Cell Lung cell line, single concentration
Assay data:2494 Active, 74525 Tested
NCI human tumor cell line growth inhibition assay. Data for the OVCAR-5 Non-Small Cell Lung cell line, single concentration
Assay data:1901 Active, 76429 Tested
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