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Compound was evaluated for the inhibition of Trypanosoma cruzi LAP (at 30 M)
Assay data:33 Active, 3327 Tested
Summary
Inhibition of SARS-CoV-2 3CL-Pro proteolytic cleavage of a dual-labeled substrate by FRET at 1mM DTT.
Assay data:24 Active, 19 Activity ≤ 1 µM, 64 Tested
SummaryRelated BioAssays by Target
Human kisspeptin (KISS1R) small molecule agonists, calcium flux assay in KISS1R-HEK293 cells: Summary
Assay data:16 Active, 9667 Tested
SummaryCompounds, ActiveRelated BioAssays by DepositorRelated BioAssays by Same Project
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells: Summary
Assay data:109 Active, 9667 Tested
G protein-coupled receptor (GPCR) small molecule agonists, calcium flux assay: HEK293 wild type cell line counter screen
Assay data:47 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Human kisspeptin (KISS1R) small molecule agonists, calcium flux assay in KISS1R-HEK293 cells
Assay data:55 Active, 2 Activity ≤ 1 nM, 10 Activity ≤ 1 µM, 9667 Tested
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells
Assay data:169 Active, 2 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 9667 Tested
High-throughput screening primary assay to identify small molecule activators of human guanylyl cyclase B (GC-B) receptor activity
Assay data:399 Active, 370620 Tested
SummaryCompounds, Active
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: qHTS cell viability counter screen in human keratinocytes
Assay data:683 Active, 47 Activity ≤ 1 µM, 9667 Tested
Increase the activity of the Burkholderia fixLJ 2-component system
Assay data:87 Active, 28704 Tested
SummaryCompounds, ActivePubMed Citation
Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Assay data:281 Active, 189401 Tested
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Fluorescence-based screening to identify small molecule inhibitors of Plasmodium falciparum apicoplast DNA polymerase (Pf-apPOL).
Assay data:523 Active, 206263 Tested
NCI human tumor cell line growth inhibition assay. Data for the KM12 Non-Small Cell Lung cell line, single concentration
Assay data:3444 Active, 76734 Tested
SummaryCompounds, ActiveRelated BioAssays by Depositor
NCI human tumor cell line growth inhibition assay. Data for the HCC-2998 Non-Small Cell Lung cell line, single concentration
Assay data:3073 Active, 74254 Tested
NCI human tumor cell line growth inhibition assay. Data for the HCT-116 Non-Small Cell Lung cell line, single concentration
Assay data:5131 Active, 77082 Tested
NCI human tumor cell line growth inhibition assay. Data for the SW-620 Non-Small Cell Lung cell line, single concentration
Assay data:3653 Active, 76840 Tested
NCI human tumor cell line growth inhibition assay. Data for the MDA-MB-435 Non-Small Cell Lung cell line, single concentration
Assay data:5608 Active, 76570 Tested
NCI human tumor cell line growth inhibition assay. Data for the BT-549 Non-Small Cell Lung cell line, single concentration
Assay data:2768 Active, 73031 Tested
NCI human tumor cell line growth inhibition assay. Data for the T-47D Non-Small Cell Lung cell line, single concentration
Assay data:3353 Active, 74196 Tested
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