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Anti-cancer activity against human T24 cells
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Summary
Inhibition of pyruvate carboxylase in human HCCLM3 cell lysate measured upto 24 hrs by PC assay kit
Assay data:7 Active, 7 Activity ≤ 1 µM, 16 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of pyruvate carboxylase in human HepG2 cell lysate measured upto 24 hrs by PC assay kit
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Inhibition of pyruvate carboxylase in human HepG2 cells measured upto 24 hrs by PC assay kit
Antiproliferative activity against human HCCLM3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 15 Tested
Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human MHCC97 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Assay data:7 Active, 1 Activity ≤ 1 µM, 15 Tested
Antiproliferative activity against human MCF7 cells after 48 hrs by sulforhodamine B assay
Assay data:11 Active, 9 Activity ≤ 1 µM, 11 Tested
Inhibition of bovine tubulin polymerization
Assay data:27 Active, 22 Activity ≤ 1 µM, 29 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of tubulin polymerization
Assay data:23 Active, 14 Activity ≤ 1 µM, 48 Tested
Cytotoxic concentration required to inhibit 50% cell growth in SKMEL-5 melanoma cell lines
Assay data:27 Active, 5 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 72 Tested
Concentration required for 50% inhibition of P388 murine leukemia cell growth in MTT assay
Assay data:6 Active, 5 Activity ≤ 1 µM, 8 Tested
Cytotoxic concentration required to inhibit 50% cell growth in MLM melanoma cell lines
Assay data:17 Active, 3 Activity ≤ 1 nM, 12 Activity ≤ 1 µM, 72 Tested
Cytotoxic concentration required to inhibit 50% cell growth in MCF-7 breast carcinoma cell lines
Assay data:26 Active, 3 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 72 Tested
Compound was tested for the inhibition of L1210 leukemia cells growth in mice
Cytotoxic concentration required to inhibit 50% cell growth in HT-29 colon adenocarcinoma cell lines
Assay data:24 Active, 4 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 72 Tested
Cytotoxicity of compound against HL-60 human leukemia cells
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
Cytotoxic concentration required to inhibit 50% cell growth in A-549 lung carcinoma cell lines
Assay data:24 Active, 3 Activity ≤ 1 nM, 16 Activity ≤ 1 µM, 72 Tested
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