Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of human 11beta-HSD1 expressed in HEK293 cells measured after 10 mins
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryRelated BioAssays by Target
Human gonadotropin-releasing hormone receptor (GnRHR) small molecule agonists, calcium flux assay in GnRHR-HEK293 cells
Assay data:169 Active, 2 Activity ≤ 1 nM, 27 Activity ≤ 1 µM, 9667 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Same Project
Nuclear factor erythroid 2-related factor 2/antioxidant responsive element (Nrf2/ARE) small molecule agonists: qHTS cell viability counter screen in human keratinocytes
Assay data:683 Active, 47 Activity ≤ 1 µM, 9667 Tested
Inhibition of SHP2 (unknown origin)
Assay data:10 Active, 5 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Anti-asthmatic activity against ovalbumin-induced asthmatic mouse model assessed as infiltration of inflammatory cells in the perivascular and peribronchiolar region of lungs at 20 mg/kg, po administered once daily for 7 days by H and E staining based light microscopic analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed Citation
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Activation of AMPK in human Huh-7 cells assessed as increase in AMPK phosphorylation at Thr172 residue at 10 uM measured after 12 hrs by Western blot analysis
Assay data:20 Active, 20 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Neuroprotective activity against CoCl2-induced neuronal injury in rat PC12 cells
Assay data:6 Active, 3 Activity ≤ 1 µM, 10 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Validation qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:265 Active, 171 Activity ≤ 1 µM, 15637 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Confirmatory qHTS for antagonist of cAMP-regulated guanine nucleotide exchange factor 4 (EPAC2)
Assay data:691 Active, 129 Activity ≤ 1 µM, 5387 Tested
Inhibition of human microsomal 11beta-HSD1 overexpressed in HEK293 cells using [3H]-cortisone as substrate assessed as formation of [3H]-cortisol using [3H]cortisone by scintillation proximity assay in presence of NADPH
Assay data:3 Active, 1 Activity ≤ 1 µM, 6 Tested
Inhibition of mouse microsomal 11beta-HSD1 overexpressed in HEK293 cells using [3H]-cortisone as substrate assessed as formation of [3H]-cortisol using [3H]cortisone by scintillation proximity assay in presence of NADPH
Assay data:5 Active, 3 Activity ≤ 1 µM, 6 Tested
Inhibition of recombinant mouse Glyoxalase-1 expressed in Escherichia coli BL21 (DE3) pLysS cells using GSH and MGO as substrate by Dixon plot
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Antiviral activity against EBV infected in human Raji cells assessed as reduction in viral genome copy numbers by qRT-PCR analysis
Assay data:1 Active, 2 Tested
Inhibition of hla expression in methicillin-resistant Staphylococcus aureus at 0.5 times MIC by qRT-PCR analysis relative to control
Assay data:2 Active, 2 Tested
Inhibition of seaR expression in methicillin-resistant Staphylococcus aureus at 0.5 times MIC by qRT-PCR analysis relative to control
Upregulation of hla expression in Staphylococcus aureus ATCC 25923 at 0.5 times MIC by qRT-PCR analysis relative to control
Upregulation of seaR expression in Staphylococcus aureus ATCC 25923 at 0.5 times MIC by qRT-PCR analysis relative to control
Upregulation of yqhB expression in Bacillus subtilis ATCC 6051 at 0.5 times MIC by qRT-PCR analysis relative to control
Upregulation of yhdT expression in Bacillus subtilis ATCC 6051 at 0.5 times MIC by qRT-PCR analysis relative to control
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on