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Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 4 (GPX4)
Assay data:258 Active, 16 Activity ≤ 1 µM, 11046 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
Primary qHTS Assay for Inhibitors of Recombinant Selenoprotein Glutathione Peroxidase 1 (GPX1)
Assay data:186 Active, 9 Activity ≤ 1 µM, 11353 Tested
Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry
Assay data:368 Active, 78 Activity ≤ 1 µM, 5114 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Depositor
Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry
Assay data:158 Active, 29 Activity ≤ 1 µM, 5114 Tested
Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: luciferase cell-based qHTS assay
Assay data:2039 Active, 244 Activity ≤ 1 µM, 5242 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by DepositorRelated BioAssays by Target
Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: luciferase cell-based qHTS assay
Assay data:2147 Active, 1 Activity ≤ 1 nM, 377 Activity ≤ 1 µM, 5242 Tested
Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: luciferase cell-based qHTS assay
Assay data:1774 Active, 1 Activity ≤ 1 nM, 362 Activity ≤ 1 µM, 5242 Tested
Primary qHTS for Vero E6 cytotoxicity: counterscreen for inhibitors of SARS-S pseudo-typed particle cell entry
Assay data:20 Active, 14 Activity ≤ 1 µM, 2678 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Depositor
Primary qHTS for inhibitors of MERS-S pseudo-typed particle cell entry
Assay data:88 Active, 17 Activity ≤ 1 µM, 2678 Tested
Primary qHTS for Huh7 cytotoxicity: counterscreen for inhibitors of MERS-S pseudotyped particle cell entry
Assay data:25 Active, 8 Activity ≤ 1 µM, 2678 Tested
Primary qHTS for inhibitors of SARS-S pseudo-typed particle cell entry
Assay data:73 Active, 72 Activity ≤ 1 µM, 2678 Tested
Inhibition of DLODP in human HepG2 microsomal membrane assessed as reduction in [3H]OSP production using Glc3-0[3H]Man9-5GlcNAc2-PP-dolichol as substrate at pH 5.5 measured after 20 to 60 mins by scintillation counting
Assay data:8 Active, 3 Activity ≤ 1 µM, 17 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed Citation
Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow CO2 hydrase assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 41 Tested
Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assay
Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 35 Tested
Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 41 Tested
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay
Assay data:2 Active, 1 Activity ≤ 1 µM, 35 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assay
Assay data:7 Active, 4 Activity ≤ 1 µM, 35 Tested
Inhibition of recombinant Vibrio cholerae beta-carbonic anhydrase expressed in competent Escherichia coli BL21(DE3) cells preincubated for 15 mins by stopped-flow CO2 hydration assay
Assay data:1 Active, 39 Tested
SummaryCompounds, ActivePubMed Citation
Inhibition of Vibrio cholerae alpha-carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydration assay
Assay data:2 Active, 34 Tested
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