Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Inhibition of GLI1 (unknown origin) transcriptional activity
Assay data:4 Active, 3 Activity ≤ 1 µM, 4 Tested
SummaryRelated BioAssays by Target
Inhibition of GLI1-mediated transcriptional activity in human HaCaT cells coexpressing luciferase
Assay data:1 Active, 3 Tested
Inhibition of GLI in SAG stimulated human Daoy cells assessed as prevention of Hedgehog signaling by measuring reduction of PTCH1 expression at 20 uM in presence of siRNA for SUFU by Western blot analysis
Assay data:1 Active, 1 Tested
SummaryCompounds, ActiveRelated BioAssays by Target
Inhibition of GLI in SAG stimulated human Daoy cells assessed as prevention of Hedgehog signaling by measuring reduction of GLI expression at 20 uM in presence of siRNA for SUFU by Western blot analysis
Inhibition of GLI1 transcriptional activity in human A375 cells assessed as downregulation of Cyclin D1 mRNA expression at 5 uM incubated for 48 hrs by qPCR analysis
Assay data:5 Active, 5 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of GLI1 transcriptional activity in human A375 cells assessed as downregulation of GLI2 mRNA expression at 5 uM incubated for 48 hrs by qPCR analysis
Inhibition of GLI1 transcriptional activity in human A375 cells assessed as downregulation of HIP1 mRNA expression at 5 uM incubated for 48 hrs by qPCR analysis
Inhibition of GLI1 transcriptional activity in human A375 cells assessed as downregulation of PTCH1 mRNA expression at 5 uM incubated for 48 hrs by qPCR analysis
Inhibition of GLI1 transcriptional activity in human A375 cells assessed as downregulation of GLI1 mRNA expression at 5 uM incubated for 48 hrs by qPCR analysis
Inhibition of GLI1 transcriptional activity in HH-responsive mouse NIH3T3 cells assessed as reduction in SAG-induced luciferase activity at 5 uM incubated for 48 hrs by luciferase reporter gene assay relative to control
Assay data:23 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of GLI1 transcriptional activity in HH-responsive mouse NIH3T3 cells assessed as reduction in GLI1 protein expression at 5 uM incubated for 48 hrs in presence of SAG by Western blot analysis
Assay data:12 Active, 23 Tested
Inhibition of Gli1 (unknown origin) expression in mouse Shh Light2 cells at 100 uM by Western blot analysis
Assay data:3 Tested
Inhibition of Gli1 (unknown origin) expression in mouse Shh Light2 cells at 1 to 100 uM by Western blot analysis
Assay data:2 Tested
Inhibition of Shh-N-induced Gli1 (unknown origin) expressed in mouse Shh Light2 cells assessed as Gli1-mediated mediated transcription up to 50 uM incubated for 30 hrs by firefly luciferase assay
Assay data:1 Tested
Inhibition of Shh-N-induced Gli1 (unknown origin) expressed in mouse Shh Light2 cells assessed as Gli1-mediated mediated transcription at 50 uM incubated for 30 hrs by firefly luciferase assay
Assay data:4 Tested
Inhibition of Shh-N-induced Gli1 (unknown origin) expressed in mouse Shh Light2 cells assessed as Gli1-mediated mediated transcription incubated for 30 hrs by firefly luciferase assay
Assay data:1 Active, 2 Tested
Inhibition of Gli1 (unknown origin) expression in mouse Shh Light2 cells at 25 to 50 uM by Western blot analysis
Assay data:2 Active, 2 Tested
Inhibition of SAG-induced Gli1 (unknown origin) expressed in mouse Shh Light2 cells at 10 to 50 uM incubated for 30 hrs by firefly luciferase assay
Inhibition of Gli1 (unknown origin) expression in mouse Shh Light2 cells at 50 uM in presence of SAG by Western blot analysis
Inhibition of GLI1/GLI2 in mouse Shh Light2 cells assessed as reduction in endogenous hedgehog signalling in presence of Smo agonist SAG by luciferase reporter gene assay
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on