Related BioAssays, by Target Similarity (List) for PubChem BioAssay (S - PubChem BioAssay - NCBI

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Items: 13

Select item 13452871.

Human Malonyl-CoA decarboxylase (Decarboxylases)

Source:: IUPHAR/BPS Guide to PHARMACOLOGY

Protein Target:: malonyl-CoA decarboxylase, mitochondrial

Assay data:1 Active, 1 Tested

AID:: 1345287

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 5175372.

Inhibition of MCD in mouse hepatocytes by whole cell assay

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:9 Active, 6 Activity ≤ 1 µM, 11 Tested

AID:: 517537

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5175363.

Inhibition of human MCD

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:53 Active, 4 Activity ≤ 1 nM, 53 Activity ≤ 1 µM, 53 Tested

AID:: 517536

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3110364.

Inhibition of human recombinant MCD

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:75 Active, 75 Activity ≤ 1 µM, 75 Tested

AID:: 311036

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 3060365.

Inhibition of MBP fused human MCD

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:32 Active, 15 Activity ≤ 1 µM, 33 Tested

AID:: 306036

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2681326.

Inhibition of malonyl-coenzyme A decarboxylase

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:27 Active, 26 Activity ≤ 1 µM, 27 Tested

AID:: 268132

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2677287.

Inhibition of MCD

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:27 Active, 23 Activity ≤ 1 µM, 27 Tested

AID:: 267728

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 2612938.

Increase in glucose oxidation rate in ischemic pig heart

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:1 Active, 1 Tested

AID:: 261293

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 2612929.

Glucose oxidation rate in isolated working hearts of Sprague-Dawley rat at 50 uM relative to DMSO

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:1 Tested

AID:: 261292

Summary PubMed Citation Related BioAssays by Target

Select item 26129110.

Glucose oxidation rate in isolated working hearts of Sprague-Dawley rat at 20 uM relative to DMSO

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:12 Tested

AID:: 261291

Summary PubMed Citation Related BioAssays by Target

Select item 26128611.

Inhibition of MCD at 10 uM

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:3 Tested

AID:: 261286

Summary PubMed Citation Related BioAssays by Target

Select item 26128512.

Inhibition of MCD

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:56 Active, 5 Activity ≤ 1 nM, 51 Activity ≤ 1 µM, 56 Tested

AID:: 261285

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 25970113.

Inhibitory activity against recombinant human MCD MBP fusion protein

Source:: ChEMBL

Protein Target:: Malonyl-CoA decarboxylase, mitochondrial

Assay data:37 Active, 20 Activity ≤ 1 µM, 75 Tested

AID:: 259701

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (10)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (2)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (8)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Confirmatory (8)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations

Depositor Category

Literature Extraction (13)
BioAssays extracted from the literature

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Related BioAssays, by Target Similarity (List) for PubChem BioAss... (13)
Related BioAssays, by Target Similarity (List) for PubChem BioAssay (Select 517537)
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PubChem BioAssay
Gene Links for Protein (Select 1111244442) (1)
Gene
ACVR1 activin A receptor type 1 [Homo sapiens]
ACVR1 activin A receptor type 1 [Homo sapiens]
Gene ID:90

Gene
Sus scrofa isolate TJ Tabasco breed Duroc chromosome 12, Sscrofa11.1, whole geno...
Sus scrofa isolate TJ Tabasco breed Duroc chromosome 12, Sscrofa11.1, whole genome shotgun sequence
gi|1154346159|gnl|ASM:GCF_000000215 2|ref|NC_010454.4||gpp|GPC_000002885.1||gnl|NCBI_GENOMES|22049

Nucleotide

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