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Cross screening panel
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryRelated BioAssays by Target
Assay data:1 Active, 1 Tested
Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Assay data:1 Tested
Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate at 10 uM preincubated for 10 mins followed by NADPH addition and measured after 15 mins by LC-MS/MS analysis
Inhibition of CYP3A4 (unknown origin)
Inhibition of CYP2C8 (unknown origin)
Inhibition of CYP1A2 (unknown origin)
Inhibition of CYP2C9 (unknown origin)
Inhibition of CYP2D6 (unknown origin)
Assay data:3 Tested
Assay data:1 Active, 3 Tested
Inhibition of CYP2C19 (unknown origin)
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