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NanoBRET assay (FLT3, SGC Frankfurt)
Assay data:2 Tested
SummaryRelated BioAssays by Target
PDGFRA Invitrogen Lab (UK) kinase screen (BI)
Assay data:1 Tested
Inhibition of PDGFRa (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of FLT3 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MV4-11 cells harboring FLT3-ITD mutant at 0.3 uM incubated for 4 hrs by Western blot analysis
Assay data:1 Active, 1 Tested
Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MOLM-14 cells harboring FLT3-ITD mutant at 1 uM incubated for 4 hrs by Western blot analysis
Inhibition of FLT3 autophosphorylation at Tyr589/591 residue in human MOLM-13 cells harboring FLT3-ITD mutant at 1 uM incubated for 4 hrs by Western blot analysis
Inhibition of FLT3 ITD mutant (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of FLT3 (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay
Inhibition of PDGFRalpha (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay
Inhibition of PDGFRbeta (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay
Inhibition of KIT (unknown origin) preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay
Inhibition of FLT3 ITD mutant (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control
Inhibition of FLT3 (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control
Inhibition of PDGFRalpha (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control
Inhibition of PDGFRbeta (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control
Inhibition of KIT (unknown origin) assessed as residual activity at 1 uM preincubated for 60 mins followed by ATP addition and measured after 1 hr by ADP-Glo assay relative to control
Inhibition of Flt3 (unknown origin) at 1 uM relative to control
Assay data:3 Tested
Inhibition of PDGFRalpha (unknown origin) at 1 uM relative to control
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