Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
MAPK1 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
MAPK1 Invitrogen Lab (UK) kinase screen (BI)
Inhibition of ERK1 (unknown origin) at 10 uM by biochemical hotspot kinase assay
Inhibition of ERK2 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Inhibition of human ERK1 assessed as residual activity at 1 uM relative to control
Inhibition of ERK1/2 pathway in human A549/Taxol cells assessed as decrease in phosphorylated ERK1/2 level at 2.5 to 5 uM incubated for 24 hrs
Assay data:1 Active, 1 Tested
Inhibition of ERK1/2 pathway in human A549/Taxol cells assessed as decrease in phosphorylated ERK1/2 level at 5 uM incubated for 24 hrs
Inhibition of ERK1/2 phosphorylation at Thr202/Tyr204 residues in human MV4-11 cells at 0.1 uM incubated for 1 hrs by immunoblotting analysis
Inhibition of doxorubicin-induced ERK1/2 activation in rat H9c2 cells assessed as reduction in ERK1/2 phosphorylation at 20 uM in presence of doxorubicin by immunoblot analysis
Assay data:5 Active, 5 Tested
Inhibition of ERK2 (unknown origin)
Binding affinity to ERK1 (unknown origin) by surface plasmon resonance assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of ERK2 (unknown origin) at 100 uM preincubated for 1 hr followed by substrate addition and measured after 1 hr by Z-lyte assay relative to control
Assay data:24 Tested
Inhibition of ERK1 (unknown origin) at 25 nM relative to control
Assay data:8 Tested
Inhibition of Erk2 (unknown origin)
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
Inhibition of Erk1 (unknown origin)
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
p38 Inhibitory Potency Assay from US Patent US11844801: "Oral compositions of MK2 pathway inhibitor for treatment of immune conditions"
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on