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Binding Assay from US Patent US20240043418: "1,3-DIHYDRO-2H-PYRROLO[3,4-C]PYRIDINE DERIVATIVES AS GABAA A5 RECEPTOR MODULATORS"
Assay data:3 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
SummaryRelated BioAssays by Target
Cross screening panel
Assay data:1 Tested
GABAA, Muscimol, Central Eurofins Panlabs panel
GABAA, Flunitrazepam, Central Eurofins Panlabs panel
GABAA, Chloride Channel, TBOB Eurofins Panlabs panel
BZD/CENTR/R Eurofins SafetyScreen44 (BI)
Compound was evaluated for inhibition of rat Gabra1 in an in vitro assay with cellular components measured by membrane filtration
Assay data:35 Active, 29 Activity ≤ 1 µM, 1200 Tested
Binding affinity towards rat Gabra1 in an in vitro assay with cellular components measured by scintillation counting
Assay data:6 Active, 1 Activity ≤ 1 µM, 532 Tested
Binding affinity towards human GABRA1 in an in vitro assay with cellular components measured by scintillation counting
Assay data:1 Active, 3 Activity ≤ 1 µM, 438 Tested
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