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Summary
Inhibition of Kv1.5 (unknown origin) by patch clamp method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activation of human Kv1.2 expressed in HEK293T cells at 10 uM by patch clamp electrophysiology method
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Effect on rat Kv1.6 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Effect on rat Kv1.5 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Effect on rat Kv1.4 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Effect on human Kv1.3 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Effect on rat Kv1.2 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Effect on rat Kv1.1 expressed in Xenopus laevis oocytes at 10 uM at holding potential of -90 mV by patch clamp electrophysiology
Inhibition of human Kv1.3 expressed in HEK293 cells assessed as inhibition of tetracyclin induced current at 30 uM at holding potential of -80 mV by patch clamp method relative to control
Assay data:21 Tested
Inhibition of human Kv1.3 expressed in HEK293 cells assessed as inhibition of tetracyclin induced current at holding potential of -80 mV by patch clamp method
Assay data:3 Active, 2 Activity ≤ 1 µM, 4 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of human Kv1.3 expressed in HEK293 cells assessed as inhibition of tetracyclin induced current at 1 uM at holding potential of -80 mV by patch clamp method relative to control
Assay data:20 Tested
Inhibition of human Kv1.5 expressed in Xenopus laevis oocytes assessed as inhibition of channel current at 10 uM at +40mV holding potential by two-electrode voltage clamp assay
Inhibition of human hKv1.5 at 30 uM comprehensive in-vitro proarrhythmia assay
Patch-Clamp Assay from US Patent US10822345: "KV1.3 inhibitors and their medical application"
Assay data:63 Active, 44 Activity ≤ 1 µM, 63 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
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