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STK4 SGC Tm panel (DSF)
Assay data:1 Tested
SummaryRelated BioAssays by Target
STK3 SGC Tm panel (DSF)
STK3 Invitrogen Lab (UK) kinase screen (BI)
Inhibition of MST2 (unknown origin) at 10 uM by biochemical hotspot kinase assay relative to control
Inhibition of STK4 (unknown origin)
Binding affinity to recombinant STK4 (unknown origin) assessed as dissociation constant by DSF assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of recombinant STK4 (unknown origin) at 10 uM by DSF assay relative to staurosporine
Binding affinity to recombinant STK4 (unknown origin) assessed as change in melting temperature at 10 uM by DSF assay
Binding affinity to recombinant STK3 (unknown origin) assessed as change in melting temperature at 10 uM by DSF assay
Inhibition of human full length wild type MST1 expressed in mammalian system at 1 uM by KINOMEscan analysis relative to control
Inhibition of STK4 (unknown origin) incubated for 90 mins in presence of ATP by microplate reader assay
Assay data:9 Active, 7 Activity ≤ 1 µM, 9 Tested
Selectivity interaction (ScanMAX (DiscoverX, competition-binding assay)) EUB0000285b STK4
Selectivity interaction (ScanMAX (DiscoverX)) EUB0000285b STK4
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