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Progesterone PR-B Eurofins Panlabs panel
Assay data:1 Tested
SummaryRelated BioAssays by Target
Binding affinity towards human PGR in an in vitro assay with cellular components measured by scintillation counting
Assay data:87 Active, 51 Activity ≤ 1 µM, 927 Tested
Binding affinity towards human PGR in an in vitro cell free assay measured by fluorescence polarization method in vitro cell free assay
Assay data:15 Active, 5 Activity ≤ 1 µM, 357 Tested
Antagonist activity at human PGR in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:29 Active, 4 Activity ≤ 1 µM, 850 Tested
Agonist activity at human PGR in an in vitro cell free assay measured by time-resolved fluorescence resonance energy transfer method
Assay data:55 Active, 39 Activity ≤ 1 µM, 930 Tested
Antagonist activity at progesterone receptor (unknown origin)
Assay data:5 Active, 5 Activity ≤ 1 µM, 5 Tested
Activation of human progesterone receptor transfected in human PC-3 cells incubated for 16 hrs by luciferase based analysis
Assay data:2 Tested
Agonist activity at human PR-beta expressed in U2OS cells by PathHunter assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at human PR-alpha expressed in U2OS cells by PathHunter assay
Agonist activity at human PR-beta expressed in U2OS cells assessed as maximum relative efficacy at 100 uM by PathHunter assay relative to norgestrel
SummaryPubMed CitationRelated BioAssays by Target
Agonist activity at human PR-alpha expressed in U2OS cells assessed as maximum relative efficacy at 100 uM by PathHunter assay relative to norgestrel
Agonist activity at progesterone receptor (unknown origin) expressed in PC3 cells co-transfected with ARR3tk-luciferase/Renilla at 10 to 25 uM incubated for 16 hrs by luciferase reporter gene assay
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at progesterone receptor in human MCF7 cells
Assay data:14 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at progesterone receptor in human HEK293T cells by dual-Glo luciferase assay
Antagonist activity at progesterone receptor in human HEK293T cells assessed as reduction in aldosterone-induced luciferase activity by dual-Glo luciferase assay
Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity at 125 nM incubated for 72 hrs followed by substrate addition measured after 24 hrs by alkaline phosphatase assay
Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as fold increase in alkaline phosphatase activity at 25 nM incubated for 72 hrs followed by substrate addition measured after 24 hrs by alkaline phosphatase assay relative to control
Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as fold increase in alkaline phosphatase activity at 1 nM incubated for 72 hrs followed by substrate addition measured after 24 hrs by alkaline phosphatase assay relative to control
Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity incubated for 72 hrs followed by substrate addition measured after 24 hrs by alkaline phosphatase assay
Assay data:2 Active, 1 Activity ≤ 1 nM, 3 Activity ≤ 1 µM, 3 Tested
Agonist activity at PR in human T47D cells using p-nitrophenyl phosphate as substrate assessed as induction of alkaline phosphatase activity at 1 nM incubated for 72 hrs followed by substrate addition measured after 24 hrs by alkaline phosphatase assay relative to control
Assay data:3 Tested
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