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ACC2 Enzyme Activity Assay from US Patent US11186587: "Compound as ACC inhibitor and use thereof"
Assay data:19 Active, 19 Activity ≤ 1 µM, 19 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by DepositorRelated BioAssays by Target
ACC1 Enzyme Activity Assay from US Patent US11186587: "Compound as ACC inhibitor and use thereof"
Assay data:31 Active, 8 Activity ≤ 1 nM, 32 Activity ≤ 1 µM, 32 Tested
etermination of IC50 of Inhibition of Enzymatic Activity of ACC1 and ACC2 by the Compound of the Present Disclosure from US Patent US11142531: "Cyano substituted heteroarylpyrimidinone derivative, preparation method and use thereof"
Assay data:13 Active, 13 Activity ≤ 1 µM, 13 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMRelated BioAssays by Target
In Vitro Acetyl-CoA Carboxylase (ACC) Inhibition Assay from US Patent US10995099: "Compounds and their uses as ACC inhibitors"
Assay data:52 Active, 6 Activity ≤ 1 nM, 59 Activity ≤ 1 µM, 59 Tested
ACCase Enzymatic Assay from US Patent US10995070: "Acetyl-CoA carboxylase modulators"
Assay data:12 Active, 5 Activity ≤ 1 µM, 15 Tested
Kinase Assay from US Patent US10759812: "Thienopyrimidine derivative and use thereof in medicine"
Assay data:15 Active, 6 Activity ≤ 1 nM, 15 Activity ≤ 1 µM, 15 Tested
Spectrophotometric 384 Well Assay from US Patent US9340510: "Tetrahydroisoquinoline derivatives, pharmaceutical compositions and uses thereof"
Assay data:245 Active, 244 Activity ≤ 1 µM, 245 Tested
Human ACC2 Enzyme Assay from US Patent US9278925: "Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one"
Assay data:10 Active, 4 Activity ≤ 1 µM, 10 Tested
Human ACC1 Enzyme Assay from US Patent US9278925: "Substituted 3-(biphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5]dec-3-en-2-one"
Assay data:10 Active, 10 Activity ≤ 1 µM, 10 Tested
Spectrophotometric 384 Well Assay from US Patent US9278954: "Pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:149 Active, 135 Activity ≤ 1 µM, 149 Tested
ACC1 Enzyme Assay B1 from US Patent US9212140: "(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment"
Assay data:3 Active, 3 Activity ≤ 1 µM, 3 Tested
ACC2 Enzyme Assay A2 from US Patent US9212140: "(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment"
Assay data:3 Active, 2 Activity ≤ 1 µM, 3 Tested
ACC2 Enzyme Assay B2 from US Patent US9212140: "(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment"
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
ACC1 Enzyme Assay A1 from US Patent US9212140: "(5s,8s)-3-(4′-chlor-3′-fluor-4-methlybiphenyl-3-yl)-4-hydroxy-8-methoxy-1-azaspiro[4.5] dec-3-en-2-one (compound A) for treatment"
Spectrophotometric 384 Well Assay from US Patent US9169205: "Pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:197 Active, 186 Activity ≤ 1 µM, 197 Tested
Inhibition Assay from US Patent US8993586: "N1/N2-lactam acetyl-CoA carboxylase inhibitors"
Assay data:124 Active, 1 Activity ≤ 1 nM, 121 Activity ≤ 1 µM, 124 Tested
Assay data:124 Active, 118 Activity ≤ 1 µM, 124 Tested
Spectrophotometric 384 Well Assay from US Patent US8962641: "Pyrimidine-substituted pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:483 Active, 455 Activity ≤ 1 µM, 483 Tested
Spectrophotometric 384 Well Assay from US Patent US8877741: "Pyrrolidine derivatives, pharmaceutical compositions and uses thereof"
Assay data:478 Active, 472 Activity ≤ 1 µM, 478 Tested
Spectrophotometric 384 Well Assay from US Patent US8835472: "Compounds, pharmaceutical compositions and uses thereof"
Assay data:611 Active, 384 Activity ≤ 1 µM, 663 Tested
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