BioAssay by Target (List) for Gene (Select 637) - PubChem BioAssay - NCBI

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Select item 18588401.

Binding affinity to Bfl-1/Bid (unknown origin) incubated for 3 hrs by fluorescence polarization-based binding assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858840

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18588392.

Binding affinity to Mcl-1/Bid (unknown origin) incubated for 3 hrs by fluorescence polarization-based binding assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858839

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18588383.

Inhibition of Mcl-1/FITC-labelled Bid (unknown origin) protein protein interaction incubated for 20 to 60 mins by fluorescence polarisation binding assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1858838

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 18588374.

Inhibition of Mcl-1(unknown origin)/ human Bid by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858837

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18588365.

Inhibition of Bfl-1 (unknown origin)/ human Bid by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Tested

AID:: 1858836

Summary PubMed Citation Related BioAssays by Target

Select item 18588356.

Inhibition of Bcl-B (unknown origin)/ human Bid by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858835

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18588347.

Inhibition of Bcl-W(unknown origin)/ human Bid by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858834

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18588338.

Inhibition of Bcl-2 (unknown origin)/ human Bid by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: Apoptosis regulator Bcl-2; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858833

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18588279.

Binding affinity to Mcl-1/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:5 Active, 2 Activity ≤ 1 µM, 5 Tested

AID:: 1858827

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185882310.

Binding affinity to Bcl-W/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 2 Tested

AID:: 1858823

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185882211.

Binding affinity to Bcl-xL/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:2 Active, 5 Tested

AID:: 1858822

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185882112.

Binding affinity to Bcl-2/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: Apoptosis regulator Bcl-2; ...
Total:: 2

Assay data:3 Active, 6 Tested

AID:: 1858821

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185880913.

Binding affinity to Bcl-2/Bid (unknown origin) incubated for 1 min by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: Apoptosis regulator Bcl-2; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858809

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185880814.

Binding affinity to Mcl-1/FAM-labelled Bid (unknown origin) incubated for 1 min by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1858808

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185880715.

Binding affinity to Bcl-2 /Bid (unknown origin) assessed as inhibition constant by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: Apoptosis regulator Bcl-2; ...
Total:: 2

Assay data:7 Active, 6 Activity ≤ 1 µM, 7 Tested

AID:: 1858807

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185880516.

Binding affinity to human N-terminal 8xHis tagged Mcl-1/5-FAM-tagged Bid (unknown origin) assessed as inhibition constant by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858805

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185880417.

Binding affinity to human Bcl-2 (29 to 44 residues)/5-FAM-tagged Bid (unknown origin) assessed as inhibition constant by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: Apoptosis regulator Bcl-2; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858804

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185879618.

Inhibition of Bcl-xL/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:3 Active, 1 Activity ≤ 1 µM, 4 Tested

AID:: 1858796

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 185879519.

Inhibition of Bcl-2/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: Apoptosis regulator Bcl-2; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858795

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 185879420.

Inhibition of Bcl-W/Bid (unknown origin) by fluorescence polarization assay

Source:: ChEMBL

Protein Targets:: BH3-interacting domain death agonist; ...
Total:: 2

Assay data:1 Active, 1 Tested

AID:: 1858794

Summary Compounds, Active PubMed Citation Related BioAssays by Target

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Target

RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (36)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (14)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (36)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (39)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (39)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (12)
BioAssays deposited by other experimentalists

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