BioAssay by Target (List) for Gene (Select 3654) - PubChem BioAssay - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

Items: 1 to 20 of 315

<< First< Prev

Page of 16

Select item 19633671.

Biological Assays gainst IRAK1 from US Patent US20240043405: "POTENT AND SELECTIVE IRREVERSIBLE INHIBITORS OF IRAK1"

Source:: BindingDB

Protein Targets:: Interleukin-1 receptor-associated kinase 1; ...
Total:: 1

Assay data:21 Active, 20 Activity ≤ 1 µM, 21 Tested

AID:: 1963367

Summary Related BioAssays by Target

Select item 19565232.

Inhibition of human IRAK1 using biotinylated FGLARFSRFAGSSPSQSSMVARTQTVRGT peptide as substrate incubated for 1 hr in presence of ATP by ELISA assay

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1956523

Summary Related BioAssays by Target

Select item 19490243.

Inhibition of IRAK1 (unknown origin) by Ambit kinase assay

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1949024

Summary Related BioAssays by Target

Select item 19483614.

Inhibition of IRAK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1948361

Summary Related BioAssays by Target

Select item 19431025.

Inhibition of IRAK1 (unknown origin) in presence of 25 uM ATP

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested

AID:: 1943102

Summary Related BioAssays by Target

Select item 19215546.

Inhibition of IRAK-1 (unknown origin)

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1921554

Summary Related BioAssays by Target

Select item 19197867.

Kinase Inhibitory Assay from US Patent US20230303563: "MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF"

Source:: BindingDB

Protein Targets:: Interleukin-1 receptor-associated kinase 1; ...
Total:: 3

Assay data:91 Active, 87 Activity ≤ 1 nM, 91 Activity ≤ 1 µM, 91 Tested

AID:: 1919786

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19191888.

IC50 Kinase Assays from US Patent US11542261: "Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors"

Source:: BindingDB

Protein Targets:: GTPase NRas; ...
Total:: 8

Assay data:50 Active, 8 Activity ≤ 1 nM, 45 Activity ≤ 1 µM, 50 Tested

AID:: 1919188

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 19191879.

Kinase Assay from US Patent US11542261: "Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors"

Source:: BindingDB

Protein Targets:: Cyclin-H; ...
Total:: 4

Assay data:8 Active, 7 Activity ≤ 1 nM, 8 Activity ≤ 1 µM, 8 Tested

AID:: 1919187

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191918610.

HotSpot Assay from US Patent US11542261: "Substituted Imidazo[1,2-a]-pyridines as IRAK 1/4 and FLT3 inhibitors"

Source:: BindingDB

Protein Targets:: Cyclin-H; ...
Total:: 10

Assay data:30 Active, 6 Activity ≤ 1 nM, 30 Activity ≤ 1 µM, 30 Tested

AID:: 1919186

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191918111.

Z′-LYTE Kinase Assay from US Patent US11542251: "IRAK degraders and uses thereof"

Source:: BindingDB

Protein Targets:: Interleukin-1 receptor-associated kinase 1; ...
Total:: 2

Assay data:6 Active, 6 Activity ≤ 1 µM, 6 Tested

AID:: 1919181

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 191917312.

IRAK1 Enzymatic Assay from US Patent US11542246: "Quinoline compounds as IRAK inhibitors and uses thereof"

Source:: BindingDB

Protein Targets:: Interleukin-1 receptor-associated kinase 1; ...
Total:: 1

Assay data:4 Active, 1 Activity ≤ 1 µM, 5 Tested

AID:: 1919173

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Depositor Related BioAssays by Target

Select item 191547913.

Selectivity interaction (KinomeScan (DiscoverX, competition-binding assay)) EUB0000596aBDA IRAK1

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1915479

Summary Compounds, Active Compounds, activity ≤ 1 µM Related BioAssays by Target

Select item 189458314.

Inhibition of IRAK1 (unknown origin)

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 1894583

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 188006315.

Inhibition of IRAK1 (unknown origin) at 1 uM by kinase-profiling analysis

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1880063

Summary PubMed Citation Related BioAssays by Target

Select item 188004216.

Inhibition of IRAK1 (unknown origin) by biochemical assay

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Activity ≤ 1 µM, 1 Tested

AID:: 1880042

Summary Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 183572917.

IRAK1 DiscoveRx kinase panel

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1835729

Summary Related BioAssays by Target

Select item 183500518.

IRAK1(h) Kinase panel

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1835005

Summary Related BioAssays by Target

Select item 183476519.

IRAK1(h) Millipore kinase panel

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1834765

Summary Related BioAssays by Target

Select item 183417220.

Inhibition of IRAK1 (unknown origin) at 1 uM

Source:: ChEMBL

Protein Target:: Interleukin-1 receptor-associated kinase 1

Assay data:1 Tested

AID:: 1834172

Summary PubMed Citation Related BioAssays by Target

<< First< Prev

Page of 16

Supplemental Content

Filters: Manage Filters

Refine your results

• What's this?

Target

Proteins (2)
BioAssays with protein sequences specified as targets
RNAi Target, Active (7)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (72)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (5)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (54)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (85)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (63)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (243)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (72)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (8)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (215)
BioAssays extracted from the literature
NIH MLP (2)
BioAssays deposited by the NIH Molecular Libraries Program
Other (97)
BioAssays deposited by other experimentalists

Actions on your results

View or Download BioAssay in PubChem

Find related data

Recent activity

Clear Turn Off Turn On

BioAssay by Target (List) for Gene (Select 3654) (315)
PubChem BioAssay

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Chemicals & Bioassays > PubChem BioAssay