BioAssay by Target (List) for Gene (Select 2568) - PubChem BioAssay - NCBI

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Select item 19124081.

Binding affinity to GABAA receptor (unknown origin) at 10000 nM by radioligand displacement assay relative to control

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1912408

Summary PubMed Citation Related BioAssays by Target

Select item 18850982.

Binding affinity to GABA A receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:2 Active, 2 Tested

AID:: 1885098

Summary Compounds, Active PubMed Citation Related BioAssays by Target

Select item 18802033.

Inhibition of GABA-A receptor (unknown origin)

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:4 Tested

AID:: 1880203

Summary PubMed Citation Related BioAssays by Target

Select item 18776404.

Inhibition of GABAA receptor (unknown origin) at 50 uM by radioligand receptor binding assay relative to control

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:20 Tested

AID:: 1877640

Summary PubMed Citation Related BioAssays by Target

Select item 17913975.

GABAA CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1791397

Summary Related BioAssays by Target

Select item 17913956.

GABAA BZD (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1791395

Summary Related BioAssays by Target

Select item 17913777.

Cl- channel CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1791377

Summary Related BioAssays by Target

Select item 17912818.

GABAA CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1791281

Summary Related BioAssays by Target

Select item 17912739.

BZD (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1791273

Summary Related BioAssays by Target

Select item 178876110.

Cl- channel CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788761

Summary Related BioAssays by Target

Select item 178869911.

BZD (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788699

Summary Related BioAssays by Target

Select item 178867012.

BZD (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788670

Summary Related BioAssays by Target

Select item 178861313.

Cl- channel (GABA-gated) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788613

Summary Related BioAssays by Target

Select item 178846614.

BZD (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788466

Summary Related BioAssays by Target

Select item 178840715.

Cl- channel (GABA-gated) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788407

Summary Related BioAssays by Target

Select item 178833316.

Benzodiazepine (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788333

Summary Related BioAssays by Target

Select item 178825417.

BZD (central) Ligand binding assay

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788254

Summary Related BioAssays by Target

Select item 178823818.

Cl- channel CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788238

Summary Related BioAssays by Target

Select item 178820719.

BZD (central) CEREP ligand profiling

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1788207

Summary Related BioAssays by Target

Select item 178719020.

Cl- channel CEREP screen

Source:: ChEMBL

Protein Targets:: Gamma-aminobutyric acid receptor subunit alpha-1; ...
Total:: 16

Assay data:1 Tested

AID:: 1787190

Summary Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets
RNAi Target, Active (6)
BioAssays with gene sequences specified as RNAi targets and the activity is active

BioActivity

Active Compounds (57)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (7)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (44)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (1)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (68)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (9)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (145)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (13)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (1)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (128)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (29)
BioAssays deposited by other experimentalists

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