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In vivo inhibition of RET phosphorylation in mouse KIF5B-RET BaF3 cells transfected in nude mouse assessed as tumor regression at 60 mg/kg, po qd measured after 5 hrs
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of RET in mouse BAF3(transformed) cells assessed as growth inhibition after 72 hrs by CCK8 assay
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of RET in mouse BAF3 cells harboring CCDC6-RET fusion protein assessed as suppression of AKT phosphorylation after 2 hrs by Western blot method
Assay data:1 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of RET in mouse BAF3 cells harboring CCDC6-RET fusion protein assessed as suppression of STAT3 phosphorylation after 2 hrs by Western blot method
Inhibition of RET phosphorylation in mouse BAF3 cells harboring CCDC6-RET fusion protein after 2 hrs by Western blot method
Inhibition of RET in mouse BAF3 cells harboring CCDC6-RET fusion protein assessed as suppression of RET phosphorylation after 2 hrs by Western blot method
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of Tel-fused RET in mouse BA/F3 cells
Assay data:6 Active, 4 Activity ≤ 1 µM, 6 Tested
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