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Platelet-Derived Growth Factor (PDGF) Eurofins-Panlabs radioligand binding assay
Assay data:1 Tested
SummaryRelated BioAssays by Target
Inhibition of PDGFRA in mouse BAF3(transformed) cells assessed as growth inhibition after 72 hrs by CCK8 assay
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Inhibition of PDGFR in mouse NIH/3T3 cells assessed as reduction in recombinant human PDGF-BB-induced cell proliferation after 42 hrs by cell titer 96 aqueous one solution based assay
Assay data:9 Active, 9 Activity ≤ 1 µM, 9 Tested
Binding affinity to mouse PDGFR at 10 uM after 180 mins by scintillation counting analysis relative to control
SummaryPubMed CitationRelated BioAssays by Target
Mouse platelet derived growth factor receptor alpha (Type III RTKs: PDGFR, CSFR, Kit, FLT3 receptor family)
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Inhibition of mouse PDGFR at 10 uM by radioligand binding assay
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Displacement of [125I]PDGF-BB from PDGF receptor in Balb/c mouse 3T3 cells at 10 uM after 180 mins
Displacement of [125I]PDGF BB from PDGFR in BALB/c mouse 3T3 cells at 10 uM after 180 mins by scintillation counting
Inhibition of PDGFR tyrosine phosphorylation in mouse NIH3T3 cells
Inhibition of PDGFR in mouse NIH/3T3 cells assessed as PDGF-stimulated Erk2 activation by immunoblotting
Assay data:2 Active, 2 Tested
Inhibition of PDGFR in mouse NIH/3T3 cells assessed as inhibition of PDGF-stimulated phospholipase C gamma phosphorylation by immunoblotting
Inhibition of PDGFR in mouse NIH/3T3 cells assessed as inhibition of PDGF-stimulated tyrosine autophosphorylation by immunoblotting
Inhibition of PDGFR autophosphorylation in mouse Swiss 3T3 fibroblast up to 10 ug/ml by immunoblotting
Assay data:20 Tested
Inhibition of PDGFR autophosphorylation in mouse Swiss 3T3 fibroblast by immunoblotting
Assay data:18 Active, 10 Activity ≤ 1 µM, 29 Tested
Inhibition of endogenous PDGFR in Swiss3T3 fibroblasts
Assay data:36 Active, 20 Activity ≤ 1 µM, 42 Tested
Inhibition of Platelet-derived growth factor receptor in P19 cells
Assay data:5 Active, 1 Activity ≤ 1 µM, 7 Tested
Inhibition of PDGF-mediated mitogenesis in Swiss 3T3 cells
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