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Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Effect on 36chloride ion influx in mouse embryo cortical neurons in absence of GABA-A at 10 uM relative to basal value
Assay data:2 Tested
SummaryPubMed CitationRelated BioAssays by Target
Effect on GABA-A-induced 36chloride ion influx in mouse embryo cortical neurons at 10 uM relative to basal value
Assay data:14 Tested
Increase in [3H]flunitrazepam binding to GABA-A receptor in mouse embryo cortical neurons
Assay data:4 Active, 3 Activity ≤ 1 µM, 14 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Binding affinity to mouse brain GABA receptor
Assay data:14 Active, 7 Activity ≤ 1 µM, 21 Tested
Ratio of binding affinity for mouse brain Gamma-aminobutyric acid GABA-A receptor and housefly Gamma-aminobutyric acid receptor; NA denotes not available
Assay data:3 Tested
Ratio of binding affinity for mouse brain Gamma-aminobutyric acid receptor and housefly Gamma-aminobutyric acid receptor
Assay data:30 Tested
Ex vivo inhibition of [35S]TBPS binding to mouse brain membranes after 30 min
Assay data:1 Tested
Ex vivo inhibition of [35S]TBPS binding to mouse brain membranes in the presence of phenobarbital after 30 min
Ex vivo inhibition of [35S]TBPS binding to mouse brain membranes in the presence of Diazepam after 30 min
In vitro inhibition of [35S]-TBPS binding to EDTA/water-dialyzed mouse brain P2 membranes
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
In vitro inhibition of [35S]TBPS binding to EDTA/water-dialyzed mouse brain P2 membranes
Assay data:1 Active, 1 Activity ≤ 1 nM, 1 Activity ≤ 1 µM, 1 Tested
In vivo percentage inhibition of flunitrazepam binding to mouse fore brain at 30 mg/kg
Activation of chloride ion uptake into mouse brain synaptoneurosomes, no net uptake at 4 nM
Activation of chloride ion uptake into mouse brain synaptoneurosomes
Assay data:9 Tested
Ex vivo inhibition of [3H]flunitrazepam binding to mouse GABA-A benzodiazepine receptor
Assay data:4 Tested
In vivo activity against GABA-A benzodiazepine receptor in mice
Assay data:5 Tested
In vivo activity against GABA-A benzodiazepine receptor in mice (No data)
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