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Inhibition of FGF induced FGFR1 autophosphorylation in mouse NIH 3T3 cells preincubated for 5 mins followed by FGF-stimulation for 5 mins in presence of [gamma-32P]ATP by SDS-PAGE based autoradiography
Assay data:1 Active, 2 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Agonist activity at FGFR1 in mouse NIH-3T3 cells assessed as increase in ERK phosphorylation at 15 uM after 10 mins by Western blot analysis
Assay data:4 Active, 5 Tested
Agonist activity at FGFR1 in mouse NIH-3T3 cells assessed as increase in Akt phosphorylation at 15 uM after 10 mins by Western blot analysis
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Inhibition of FGFR1 in mouse NIH/3T3 cells assessed as inhibition of acidic FGF-stimulated ERK2 phosphorylation by immunoblotting
Assay data:2 Active, 2 Tested
Inhibition of FGFR1 in mouse NIH/3T3 cells assessed as inhibition of acidic FGF-stimulated ERK1 phosphorylation by immunoblotting
Inhibition of FGFR1 in mouse NIH/3T3 cells assessed as inhibition of aFGF-stimulated pp90 phosphoprotein phosphorylation by immunoblotting
Inhibition of acidic FGF-stimulated FGFR1 tyrosine autophosphorylation in mouse NIH/3T3 cells by immunoblotting
Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblasts; Not measured
Assay data:6 Tested
SummaryPubMed CitationRelated BioAssays by Target
Inhibition of mouse Fibroblast growth factor receptor 1 expressed in NIH 3T3 fibroblasts
Assay data:4 Tested
Inhibition of FGF-mediated mitogenesis in Swiss 3T3 cells
Assay data:1 Tested
Inhibition of fibroblast growth factor (bFGF)-mediated autophosphorylation of FGF-R in Swiss 3T3 mouse fibroblasts
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Mean % inhibition of induced angiogenesis by Heparin-binding growth factor 2 at a peroral dose of 50 mg/kg in mice
Assay data:3 Tested
Mean % inhibition of induced angiogenesis by Heparin-binding growth factor 2 after intraperitoneal dose of 100 mg/kg in mice
Inhibition of mouse fibroblast growth factor receptor tyrosine kinase (FGFr)
Assay data:22 Active, 11 Activity ≤ 1 µM, 29 Tested
Inhibition of bFGF receptor autophosphorylation in mouse fibroblasts
Assay data:1 Active, 1 Tested
Assay data:1 Active, 4 Tested
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