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Induction of ESR2-mediated osteoblast differentiation in mouse calvarial osteoblast assessed as formation of mineralized nodule at 1 to 10 uM measured after 21 days by alizarin red staining based assay
Assay data:1 Active, 1 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Induction of ESR2-mediated osteoblast differentiation in mouse calvarial osteoblast assessed as increase in ALP activity at 1 pM measured after 48 hrs by spectrophotometric analysis
Assay data:4 Active, 4 Tested
Induction of ESR2-mediated osteoblast differentiation in mouse calvarial osteoblast assessed as increase in ALP activity at 100 pM measured after 48 hrs by spectrophotometric analysis
Induction of ESR2-mediated osteoblast differentiation in mouse calvarial osteoblast assessed as increase in ALP activity at 1 nM measured after 48 hrs by spectrophotometric analysis
Up regulation of ERbeta expression in mouse calvarial osteoblasts at 1 to 100 pM after 48 hrs by Western blot analysis
SummaryCompounds, ActiveRelated BioAssays by Target
Activation of ERbeta in mouse calvarial osteoblasts assessed as induction of mineralization by measuring increase in calcium nodules at 1 pM supplemented with fresh medium containing compounds every 48 hrs for 18 days measured on day 18 by alizarin red-S staining based colorimetric method relative to control
Assay data:1 Tested
SummaryRelated BioAssays by Target
Activation of ERbeta in mouse calvarial osteoblasts assessed as induction of osteoblast differentiation by measuring increase in ALP activity at 1 pM using PNPP as substrate after 48 hrs by colorimetric method
Agonist activity at ERbeta in mouse Melan-a cells assessed as increase in melanin content at 40 uM measured after 48 hrs in presence of ER antagonist ICI 182780
Binding affinity to ERbeta in mouse Melan-a cells
Assay data:3 Active, 3 Tested
Mouse Estrogen receptor-beta (3A. Estrogen receptors)
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Displacement of [3H]O-estradiol from ER in Swiss mouse uteri
Assay data:3 Activity ≤ 1 µM, 3 Tested
SummaryCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Ratio of [18F]-FES uptake in uterus of ERbeta KO-mouse (estrus) and ERalpha KO-mouse (nonestrus) after 30 min with [18F]FEDPN
SummaryPubMed CitationRelated BioAssays by Target
Ratio of [18F]FES uptake in ovaries of ERbeta KO-mouse (estrus) and ERalpha KO-mouse (nonestrus) after 30 min with [18F]-FEDPN
Ratio of [18F]FES uptake in uterus of ERbeta KO-mouse (estrus) and ERalpha KO-mouse (nonestrus) after 2 hr with [18F]-FEDPN
Ratio of [18F]FES uptake in uterus of ERbeta KO-mouse (estrus) and ERalpha KO-mouse (nonestrus) after 1 hr with [18F]-FEDPN
Ratio of [18F]-FES uptake in ovaries of ERbeta KO-mouse (estrus) and ERalpha KO-mouse (nonestrus) after 2 hr with [18F]FEDPN
Ratio of [18F]-FES uptake in ovaries of ERbeta KO-mouse (estrus) and ERalpha KO-mouse (nonestrus) after 1 hr with [18F]FEDPN
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