BioAssay by Target (List) for Gene (Select 12774) - PubChem BioAssay - NCBI

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Links from Gene

Items: 13

Select item 13535451.

Displacement of [125I]-RANTES from CCR5 in mouse NIH/3T3 cells after 1 hr

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:5 Active, 3 Activity ≤ 1 nM, 5 Activity ≤ 1 µM, 5 Tested

AID:: 1353545

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 12248282.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout

Source:: Iain Fraser

Assay data:762 Active, 16821 Tested

AID:: 1224828

Summary Related BioAssays by Same Project

Select item 12248263.

Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout

Source:: Iain Fraser

Assay data:1106 Active, 16821 Tested

AID:: 1224826

Summary Related BioAssays by Same Project

Select item 10532084.

A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen

Source:: Victorian Centre for Functional Genomics, Peter MacCallum Cancer Centre

Assay data:788 Active, 16789 Tested

AID:: 1053208

Summary PubMed Citation

Select item 6572285.

Binding affinity to mouse CCR5

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 657228

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 6516986.

Counter screen for HTS for Beta-2AR agonists with FAP-tagged mouse CCR5 with Powderset1

Source:: NMMLSC

Protein Target:: CCR5 [Mus musculus]

Assay data:20 Tested

AID:: 651698

Summary PubMed Citation Related BioAssays by Depositor Related BioAssays by Same Project Related BioAssays by Target

Select item 5801167.

Binding affinity to mouse CCR5

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 580116

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 5399998.

Inhibition of mouse CCR5

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Tested

AID:: 539999

Summary PubMed Citation Related BioAssays by Target

Select item 3570909.

Binding affinity to CCR5 in C57BL/6J mouse brain membrane

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 357090

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 35708910.

Binding affinity to CCR5 in NY1DD transgenic mouse brain membrane

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested

AID:: 357089

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

Select item 31465911.

Binding affinity to mouse CCR5

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Tested

AID:: 314659

Summary PubMed Citation Related BioAssays by Target

Select item 25701812.

Inhibition of mouse CCR5

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:1 Tested

AID:: 257018

Summary PubMed Citation Related BioAssays by Target

Select item 5285113.

Inhibition of RANTES binding to Chemokine receptor type 5 receptor from NIH 3T3 cells

Source:: ChEMBL

Protein Target:: C-C chemokine receptor type 5

Assay data:51 Active, 57 Activity ≤ 1 µM, 57 Tested

AID:: 52851

Summary Compounds, Active Compounds, activity ≤ 1 µM PubMed Citation Related BioAssays by Target

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Target

Proteins (1)
BioAssays with protein sequences specified as targets

BioActivity

Active Compounds (6)
BioAssays with compounds reported as biologically active
Activity (IC50, etc) ≤ 1 nM (1)
BioAssays with the active concentration of tested reagents less than 1 nanomolar
Activity (IC50, etc) ≤ 1 µM (6)
BioAssays with the active concentration of tested reagents less than 1 micromolar

Experiment Type

Summary (2)
BioAssays summarizing information from multiple assays for validated chemical probes or small molecule leads
Confirmatory (9)
Low-throughput BioAssays where the activity outcome is based on a dose-response relationship with multiple tested concentrations
Primary Screening (1)
Primary high-throughput BioAssays where the activity outcome is based on percentage inhibition from a single dose
Chemical Screens (10)
BioAssays reporting BioActivity of chemical reagents
RNAi Screens (3)
BioAssays reporting BioActivity of RNAi reagents

Assay Project (3)
BioAssays organized into assay projects based on linkage to Summary assays. Click an project below to retrieve the bioassay list for the project. Click 'All Assay Projects' to retrieve all assay projects represented by Summary assays.

Depositor Category

Literature Extraction (9)
BioAssays extracted from the literature
NIH MLP (1)
BioAssays deposited by the NIH Molecular Libraries Program
Other (3)
BioAssays deposited by other experimentalists

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