Warning: The NCBI web site requires JavaScript to function. more...
An official website of the United States government
The .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to 90 secs by FMP assay
Assay data:16 Active, 3 Activity ≤ 1 µM, 41 Tested
SummaryCompounds, ActiveCompounds, activity ≤ 1 µMPubMed CitationRelated BioAssays by Target
Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assay
Assay data:3 Active, 1 Activity ≤ 1 µM, 3 Tested
Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells at 300 uM by FMP assay
Assay data:7 Active, 7 Tested
SummaryCompounds, ActivePubMed CitationRelated BioAssays by Target
Antagonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of acetylcholine-induced effect after 30 min by FLIPR potential blue assay
Assay data:1 Active, 1 Tested
Agonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells at 300 uM after 30 min by FLIPR potential blue assay
Agonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells at >=100 uM after 30 min by FLIPR potential blue assay
Assay data:5 Active, 5 Tested
Agonist activity at recombinant mouse alpha4beta2 nAChR expressed in HEK293 cells at >=30 uM after 30 min by FLIPR potential blue assay
Assay data:2 Active, 2 Tested
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen NFkB readout
Assay data:762 Active, 16821 Tested
SummaryRelated BioAssays by Same Project
Genome-wide siRNA screen of genes regulating the Lipopolysaccharide-induced NF-kappaB and TNF-alpha responses in mouse macrophages_Primary screen TNF readout
Assay data:1106 Active, 16821 Tested
Antagonist activity at mouse alpha4beta2 nAChR transfected in HEK293 cells by FLIPR membrane potential blue (FMP) assay
Assay data:1 Active, 15 Tested
Antagonist activity at mouse alpha4/beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced activity by FLIPR membrane potential blue assay
Assay data:7 Active, 1 Activity ≤ 1 µM, 21 Tested
A screen to identify the genes that modify the response of osteosarcoma to doxorubicin in mouse - Primary Screen
Assay data:788 Active, 16789 Tested
SummaryPubMed Citation
Displacement of [125I]-epibatidine from alpha4beta2 nAChR in mouse cortical membranes
Assay data:1 Active, 1 Activity ≤ 1 µM, 1 Tested
Inhibition of mouse alpha6alpha4beta3beta2 nAChR
Assay data:2 Active, 1 Activity ≤ 1 µM, 2 Tested
Inhibition of mouse alpha4beta2* nAChR
Assay data:2 Active, 2 Activity ≤ 1 µM, 2 Tested
Activity at alpha6alpha4beta3beta2 nAChR in mouse striatal synaptosomes assessed as alpha-conotoxic MII-resistant DA release relative to control
Assay data:12 Tested
SummaryPubMed CitationRelated BioAssays by Target
Activity at alpha6alpha4beta3beta2 nAChR in mouse striatal synaptosomes assessed as alpha-conotoxic MII-resistant DA release
Assay data:8 Active, 7 Activity ≤ 1 µM, 10 Tested
Activity at alpha4beta2*nAChR in mouse striatal synaptosomes assessed as alpha-conotoxic MII-resistant DA release relative to control
Activity at alpha4beta2*nAChR in mouse striatal synaptosomes assessed as alpha-conotoxic MII-resistant DA release
Assay data:8 Active, 2 Activity ≤ 1 µM, 10 Tested
Displacement of [125I]-alpha-Conotoxin MII from alpha6beta2* nAChR in mouse olfactory tubercles, striatum and superior coliculus
Assay data:12 Active, 10 Activity ≤ 1 µM, 12 Tested
Filters: Manage Filters
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on