Alternative titles; symbols
HGNC Approved Gene Symbol: GABRR3
Cytogenetic location: 3q11.2 Genomic coordinates (GRCh38): 3:97,985,102-98,035,315 (from NCBI)
By screening a human genomic library, Bailey et al. (1999) obtained a partial sequence of GABRR3.
By genomic sequence analysis, Simon et al. (2004) obtained the complete sequence of human GABRR3. The deduced 467-amino acid protein has an N-terminal signal peptide and shares 81% amino acid identity with rat Gabrr3.
Simon et al. (2004) determined that the GABRR3 gene contains 9 exons and spans 48.3 kb.
By radiation hybrid analysis, Bailey et al. (1999) mapped the GABRR3 gene to chromosome 3q11-q13.3.
By genomic sequence analysis, Simon et al. (2004) mapped the GABRR3 gene to chromosome 3q12.1.
Gross (2019) mapped the GABRR3 gene to chromosome 3q11.2 based on an alignment of the GABRR3 sequence (GenBank NM_001105580) with the genomic sequence (GRCh38).
Bailey, M. E. S., Albrecht, B. E., Johnson, K. J., Darlison, M. G. Genetic linkage and radiation hybrid mapping of the three human GABA(c) receptor p subunit genes: GABRR1, GABRR2 and GABRR3. Biochim. Biophys. Acta 1447: 307-312, 1999. [PubMed: 10542332] [Full Text: https://doi.org/10.1016/s0167-4781(99)00167-0]
Gross, M. B. Personal Communication. Baltimore, Md. 11/20/2019.
Simon, J., Wakimoto, H., Fujita, N., Lalande, M., Barnard, E. A. Analysis of the set of GABA-A receptor genes in the human genome. J. Biol. Chem. 279: 41422-41435, 2004. [PubMed: 15258161] [Full Text: https://doi.org/10.1074/jbc.M401354200]