Entry - *615045 - HISTONE GENE CLUSTER 1, H2B HISTONE FAMILY, MEMBER K; HIST1H2BK - OMIM

 
 
* 615045

HISTONE GENE CLUSTER 1, H2B HISTONE FAMILY, MEMBER K; HIST1H2BK


Alternative titles; symbols

HISTONE GENE CLUSTER 1, H2BK
HIST1 CLUSTER, H2BK


HGNC Approved Gene Symbol: H2BC12

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,138,293-27,146,858 (from NCBI)


▼ TEXT

For background information on histones, histone gene clusters, and the H2B histone family, see HIST1H2BA (609904).

▼ Cloning and Expression

By genomic sequence analysis, Marzluff et al. (2002) identified the mouse and human HIST1H2BK genes.


▼ Mapping

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2BK.


▼ Gene Function

See HIST1H2BA (609904) for functional information on H2B histones.

▼ REFERENCES

  1. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966, related citations] [Full Text]


Creation Date:
Matthew B. Gross : 1/29/2013
Edit History:
mgross : 01/29/2013

* 615045

HISTONE GENE CLUSTER 1, H2B HISTONE FAMILY, MEMBER K; HIST1H2BK


Alternative titles; symbols

HISTONE GENE CLUSTER 1, H2BK
HIST1 CLUSTER, H2BK


HGNC Approved Gene Symbol: H2BC12

Cytogenetic location: 6p22.1     Genomic coordinates (GRCh38): 6:27,138,293-27,146,858 (from NCBI)


TEXT

For background information on histones, histone gene clusters, and the H2B histone family, see HIST1H2BA (609904).

Cloning and Expression

By genomic sequence analysis, Marzluff et al. (2002) identified the mouse and human HIST1H2BK genes.


Mapping

By genomic sequence analysis, Marzluff et al. (2002) determined that the histone gene cluster on chromosome 6p22-p21, which they called histone gene cluster-1 (HIST1), contains 55 histone genes, including HIST1H2BK.


Gene Function

See HIST1H2BA (609904) for functional information on H2B histones.

REFERENCES

  1. Marzluff, W. F., Gongidi, P., Woods, K. R., Jin, J., Maltais, L. J. The human and mouse replication-dependent histone genes. Genomics 80: 487-498, 2002. [PubMed: 12408966] [Full Text: https://linkinghub.elsevier.com/retrieve/pii/S0888754302968503]


Creation Date:
Matthew B. Gross : 1/29/2013

Edit History:
mgross : 01/29/2013



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: May 14, 2024