Entry - *612535 - THAP DOMAIN-CONTAINING PROTEIN 6; THAP6 - OMIM

 
 
* 612535

THAP DOMAIN-CONTAINING PROTEIN 6; THAP6


HGNC Approved Gene Symbol: THAP6

Cytogenetic location: 4q21.1     Genomic coordinates (GRCh38): 4:75,513,908-75,547,328 (from NCBI)


TEXT

▼ Cloning and Expression

By searching databases, Roussigne et al. (2003) identified several proteins containing an N-terminal THAP domain, including THAP6. The THAP domain of the deduced 222-amino acid THAP6 protein includes a C2CH signature, an AVPTIF box, and several other conserved amino acids. THAP6 also has a C-terminal coiled-coil domain.


▼ Mapping

Hartz (2009) mapped the THAP6 gene to chromosome 4q21.1 based on an alignment of the THAP6 sequence (GenBank AL833350) with the genomic sequence (build 36.1).

▼ REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/16/2009.

  2. Roussigne, M., Kossida, S., Lavigne, A.-C., Clouaire, T., Ecochard, V., Glories, A., Amalric, F., Girard, J.-P. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem. Sci. 28: 66-69, 2003. [PubMed: 12575992, related citations] [Full Text]


Creation Date:
Patricia A. Hartz : 1/16/2009
Edit History:
mgross : 01/16/2009

* 612535

THAP DOMAIN-CONTAINING PROTEIN 6; THAP6


HGNC Approved Gene Symbol: THAP6

Cytogenetic location: 4q21.1     Genomic coordinates (GRCh38): 4:75,513,908-75,547,328 (from NCBI)


TEXT

Cloning and Expression

By searching databases, Roussigne et al. (2003) identified several proteins containing an N-terminal THAP domain, including THAP6. The THAP domain of the deduced 222-amino acid THAP6 protein includes a C2CH signature, an AVPTIF box, and several other conserved amino acids. THAP6 also has a C-terminal coiled-coil domain.


Mapping

Hartz (2009) mapped the THAP6 gene to chromosome 4q21.1 based on an alignment of the THAP6 sequence (GenBank AL833350) with the genomic sequence (build 36.1).

REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/16/2009.

  2. Roussigne, M., Kossida, S., Lavigne, A.-C., Clouaire, T., Ecochard, V., Glories, A., Amalric, F., Girard, J.-P. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem. Sci. 28: 66-69, 2003. [PubMed: 12575992] [Full Text: https://doi.org/10.1016/S0968-0004(02)00013-0]


Creation Date:
Patricia A. Hartz : 1/16/2009

Edit History:
mgross : 01/16/2009



NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: June 11, 2024