Entry - *612534 - THAP DOMAIN-CONTAINING PROTEIN 5; THAP5 - OMIM

 
 
* 612534

THAP DOMAIN-CONTAINING PROTEIN 5; THAP5


HGNC Approved Gene Symbol: THAP5

Cytogenetic location: 7q31.1     Genomic coordinates (GRCh38): 7:108,541,759-108,569,768 (from NCBI)


TEXT

▼ Cloning and Expression

By searching databases, Roussigne et al. (2003) identified several proteins containing an N-terminal THAP domain, including THAP5. The THAP domain of the deduced 395-amino acid THAP5 protein includes a C2CH signature, an AVPTIF box, and several other conserved amino acids.


▼ Mapping

Hartz (2009) mapped the THAP5 gene to chromosome 7q31.1 based on an alignment of the THAP5 sequence (GenBank BC053634) with the genomic sequence (build 36.1).

▼ REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/16/2009.

  2. Roussigne, M., Kossida, S., Lavigne, A.-C., Clouaire, T., Ecochard, V., Glories, A., Amalric, F., Girard, J.-P. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem. Sci. 28: 66-69, 2003. [PubMed: 12575992, related citations] [Full Text]


Creation Date:
Patricia A. Hartz : 1/16/2009
Edit History:
mgross : 01/16/2009

* 612534

THAP DOMAIN-CONTAINING PROTEIN 5; THAP5


HGNC Approved Gene Symbol: THAP5

Cytogenetic location: 7q31.1     Genomic coordinates (GRCh38): 7:108,541,759-108,569,768 (from NCBI)


TEXT

Cloning and Expression

By searching databases, Roussigne et al. (2003) identified several proteins containing an N-terminal THAP domain, including THAP5. The THAP domain of the deduced 395-amino acid THAP5 protein includes a C2CH signature, an AVPTIF box, and several other conserved amino acids.


Mapping

Hartz (2009) mapped the THAP5 gene to chromosome 7q31.1 based on an alignment of the THAP5 sequence (GenBank BC053634) with the genomic sequence (build 36.1).

REFERENCES

  1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/16/2009.

  2. Roussigne, M., Kossida, S., Lavigne, A.-C., Clouaire, T., Ecochard, V., Glories, A., Amalric, F., Girard, J.-P. The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase. Trends Biochem. Sci. 28: 66-69, 2003. [PubMed: 12575992] [Full Text: https://doi.org/10.1016/S0968-0004(02)00013-0]


Creation Date:
Patricia A. Hartz : 1/16/2009

Edit History:
mgross : 01/16/2009



NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: June 4, 2024