Entry - *610730 - CHAPERONIN-CONTAINING T-COMPLEX POLYPEPTIDE 1, SUBUNIT 6B; CCT6B - OMIM

 
 
* 610730

CHAPERONIN-CONTAINING T-COMPLEX POLYPEPTIDE 1, SUBUNIT 6B; CCT6B


Alternative titles; symbols

CHAPERONIN-CONTAINING TCP1, SUBUNIT 6B
CCT-ZETA 2; CCTZ2


HGNC Approved Gene Symbol: CCT6B

Cytogenetic location: 17q12     Genomic coordinates (GRCh38): 17:34,927,861-34,961,460 (from NCBI)


TEXT

▼ Cloning and Expression

Using differential mRNA display to identify testis-specific transcripts, Ozaki et al. (1996) cloned CCT6B, which they called TSA303. The deduced 540-amino acid protein has a calculated molecular mass of 59.5 kD. CCT6B shares 83% amino acid identity with TCP20 (CCT6A; 104613), suggesting it may be a component of a chaperonin complex.

Kubota et al. (1997) cloned mouse Cct6b, which they called Cctz2. The deduced protein contains 531 amino acids. Northern blot analysis of mouse tissues detected Cct6b expression only in testis.


▼ Mapping

The International Radiation Hybrid Mapping Consortium mapped the CCT6B gene to chromosome 17 (RH71331).

▼ REFERENCES

  1. Kubota, H., Hynes, G. M., Kerr, S. M., Willison, K. R. Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1. FEBS Lett. 402: 53-56, 1997. [PubMed: 9013858, related citations] [Full Text]

  2. Ozaki, K., Kuroki, T., Hayashi, S., Nakamura, Y. Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method. Genomics 36: 316-319, 1996. [PubMed: 8812458, related citations] [Full Text]


Creation Date:
Patricia A. Hartz : 1/30/2007
Edit History:
wwang : 02/05/2007
mgross : 1/30/2007

* 610730

CHAPERONIN-CONTAINING T-COMPLEX POLYPEPTIDE 1, SUBUNIT 6B; CCT6B


Alternative titles; symbols

CHAPERONIN-CONTAINING TCP1, SUBUNIT 6B
CCT-ZETA 2; CCTZ2


HGNC Approved Gene Symbol: CCT6B

Cytogenetic location: 17q12     Genomic coordinates (GRCh38): 17:34,927,861-34,961,460 (from NCBI)


TEXT

Cloning and Expression

Using differential mRNA display to identify testis-specific transcripts, Ozaki et al. (1996) cloned CCT6B, which they called TSA303. The deduced 540-amino acid protein has a calculated molecular mass of 59.5 kD. CCT6B shares 83% amino acid identity with TCP20 (CCT6A; 104613), suggesting it may be a component of a chaperonin complex.

Kubota et al. (1997) cloned mouse Cct6b, which they called Cctz2. The deduced protein contains 531 amino acids. Northern blot analysis of mouse tissues detected Cct6b expression only in testis.


Mapping

The International Radiation Hybrid Mapping Consortium mapped the CCT6B gene to chromosome 17 (RH71331).

REFERENCES

  1. Kubota, H., Hynes, G. M., Kerr, S. M., Willison, K. R. Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1. FEBS Lett. 402: 53-56, 1997. [PubMed: 9013858] [Full Text: https://doi.org/10.1016/s0014-5793(96)01501-3]

  2. Ozaki, K., Kuroki, T., Hayashi, S., Nakamura, Y. Isolation of three testis-specific genes (TSA303, TSA806, TSA903) by a differential mRNA display method. Genomics 36: 316-319, 1996. [PubMed: 8812458] [Full Text: https://doi.org/10.1006/geno.1996.0467]


Creation Date:
Patricia A. Hartz : 1/30/2007

Edit History:
wwang : 02/05/2007
mgross : 1/30/2007



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OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.

NOTE: OMIM is intended for use primarily by physicians and other professionals concerned with genetic disorders, by genetics researchers, and by advanced students in science and medicine. While the OMIM database is open to the public, users seeking information about a personal medical or genetic condition are urged to consult with a qualified physician for diagnosis and for answers to personal questions.
OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University.
Copyright® 1966-2024 Johns Hopkins University.
Printed: June 5, 2024