Mus musculus polymerase (DNA-directed), epsilon 4 (p12 subunit) (Pole4 - Nucleotide

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Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis. [Cell Rep. 2022]
Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis.
Borel V, Boeing S, Van Wietmarschen N, Sridharan S, Hill BR, Ombrato L, Perez-Lloret J, Jackson D, Goldstone R, Boulton SJ, et al. Cell Rep. 2022 May 31; 39(9):110871.
Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication. [Cell Rep. 2020]
Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication.
Bellelli R, Youds J, Borel V, Svendsen J, Pavicic-Kaltenbrunner V, Boulton SJ. Cell Rep. 2020 May 26; 31(8):107675.
POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication. [Mol Cell. 2018]
POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication.
Bellelli R, Belan O, Pye VE, Clement C, Maslen SL, Skehel JM, Cherepanov P, Almouzni G, Boulton SJ. Mol Cell. 2018 Oct 4; 72(1):112-126.e5. Epub 2018 Sep 11.

RefSeq alternative splicing
See the other reference mRNA sequence splice variant for the Pole4 gene (NM_001370295.1).
RefSeq protein product
See the reference protein sequence for DNA polymerase epsilon subunit 4 isoform 1 (NP_080158.1).

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Protein sequence from Nucleotide coding region
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Order POLE4 cDNA clone/Protein/Antibody/RNAi [OriGene]
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Nucleotide