Homo sapiens SH2B adaptor protein 3 (SH2B3), transcript variant 1, mRN - Nucleotide

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Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity. [J Exp Med. 2024]
Rare SH2B3 coding variants in lupus patients impair B cell tolerance and predispose to autoimmunity.
Zhang Y, Morris R, Brown GJ, Lorenzo AMD, Meng X, Kershaw NJ, Kiridena P, Burgio G, Gross S, Cappello JY, et al. J Exp Med. 2024 Apr 1; 221(4). Epub 2024 Feb 28.
Acquired uniparental isodisomies involving chromosome 12 in paediatric B-cell precursor acute lymphoblastic leukaemia: Associations with chromosome 21 gains and SH2B3 mutations. [Br J Haematol. 2023]
Acquired uniparental isodisomies involving chromosome 12 in paediatric B-cell precursor acute lymphoblastic leukaemia: Associations with chromosome 21 gains and SH2B3 mutations.
Lundin-Ström KB, Biloglav A, Castor A, Olsson-Arvidsson L, Johansson B. Br J Haematol. 2023 May; 201(3):585-588. Epub 2023 Mar 10.
CTLA4, SH2B3, and CLEC16A diversely affect the progression of early islet autoimmunity in relatives of Type 1 diabetes patients. [Clin Exp Immunol. 2023]
CTLA4, SH2B3, and CLEC16A diversely affect the progression of early islet autoimmunity in relatives of Type 1 diabetes patients.
Vandewalle J, Desouter AK, Van der Auwera BJ, Tenoutasse S, Gillard P, De Block C, Keymeulen B, Gorus FK, Van de Casteele M, Belgian Diabetes Registry. Clin Exp Immunol. 2023 Mar 24; 211(3):224-232.

RefSeq alternative splicing
See 20 reference mRNA sequence splice variants for the SH2B3 gene.
RefSeq protein product
See the reference protein sequence for SH2B adapter protein 3 isoform 1 (NP_005466.1).

Protein
Protein sequence from Nucleotide coding region
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Nucleotide