Mus musculus 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Pf - Nucleotide

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Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis. [Elife. 2024]
Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Fujita S, Morikawa T, Koide S, et al. Elife. 2024 Apr 4; 12. Epub 2024 Apr 4.
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis. [J Transl Med. 2024]
Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis.
Liu XT, Huang Y, Liu D, Jiang YC, Zhao M, Chung LH, Han XD, Zhao Y, Chen J, Coleman P, et al. J Transl Med. 2024 Jan 10; 22(1):43. Epub 2024 Jan 10.
IL1R2 promotes retinal angiogenesis to participate in retinopathy of prematurity by activating the HIF1α/PFKFB3 pathway. [Exp Eye Res. 2024]
IL1R2 promotes retinal angiogenesis to participate in retinopathy of prematurity by activating the HIF1α/PFKFB3 pathway.
Zhou N, Liu L, Li Q. Exp Eye Res. 2024 Feb; 239:109750. Epub 2023 Dec 13.

RefSeq alternative splicing
See 14 reference mRNA sequence splice variants for the Pfkfb3 gene.
RefSeq protein product
See the reference protein sequence for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform 1 (NP_001171223.1).

Protein
Protein sequence from Nucleotide coding region
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Nucleotide