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Valsartan
A tetrazole derivative and ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKER that is used to treat HYPERTENSION.
Year introduced: 2016 (1993)
Angiotensin II Type 1 Receptor Blockers
Agents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.
Year introduced: 2005
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
Valine
A branched-chain essential amino acid that has stimulant activity. It promotes muscle growth and tissue repair. It is a precursor in the penicillin biosynthetic pathway.
Tetrazoles
Year introduced: 1991(1973)
Heterocyclic Compounds, 1-Ring
Organic compounds that contain a ring structure made up of carbon and one or more additional elements such as nitrogen and oxygen.
Year introduced: 1998
Heterocyclic Compounds
Cyclic compounds that include atoms other than carbon in their ring structure.
Azoles
Five membered rings containing a NITROGEN atom.
Amino Acids, Peptides, and Proteins
Amino acids and chains of amino acids connected by peptide linkages.
Amino Acids, Essential
Amino acids that are not synthesized by the human body in amounts sufficient to carry out physiological functions. They are obtained from dietary foodstuffs.
Year introduced: 1974
Amino Acids, Branched-Chain
Amino acids which have a branched carbon chain.
Year introduced: 1979
Amino Acids
Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.
Year introduced: /metabolism was AMINO ACID METABOLISM 1965
Angiotensin Receptor Antagonists
Agents that antagonize ANGIOTENSIN RECEPTORS. Many drugs in this class specifically target the ANGIOTENSIN TYPE 1 RECEPTOR.
Year introduced: 2011
Therapeutic Uses
Uses of chemicals which affect the course of conditions, diseases, syndromes or pathology to benefit the health of an individual.
Year introduced: 2004
Molecular Mechanisms of Pharmacological Action
Pharmacological activities at the molecular level of DRUGS and other exogenous compounds that are used to treat DISEASES and affect normal BIOCHEMISTRY.
Year introduced: 2008(2004)
Pharmacologic Actions
A broad category of chemical actions and uses that result in the prevention, treatment, cure or diagnosis of disease. Included here are drugs and chemicals that act by altering normal body functions, such as the REPRODUCTIVE CONTROL AGENTS and ANESTHETICS. Effects of chemicals on the environment are also included.
Year introduced: 2004(1999)
Chemical Actions and Uses
A group of pharmacologic activities, effects on living systems and the environment, and modes of employment of drugs and chemicals. They are broken into actions, which describe their effects, and uses, which describe how they are employed.
Year introduced: 1999
Cardiovascular Agents
Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume.