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Abnormal lower limb bone morphology

MedGen UID:
868066
•Concept ID:
C4022457
•
Anatomical Abnormality
Synonym: Abnormal morphology of bones of the lower limbs
 
HPO: HP:0040069

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal lower limb bone morphology

Professional guidelines

PubMed

Management of acute lesser toe pain.
Ray J, Andrews NA, Dib A, Harrelson WM, Khurana A, Singh MS, Shah A
Postgrad Med 2021 Apr;133(3):320-329. Epub 2021 Jan 18 doi: 10.1080/00325481.2021.1873581. PMID: 33406375
Treatment of Freiberg Disease.
Seybold JD, Zide JR
Foot Ankle Clin 2018 Mar;23(1):157-169. doi: 10.1016/j.fcl.2017.09.011. PMID: 29362030
Evaluation and treatment of disorders of the infrapatellar fat pad.
Dragoo JL, Johnson C, McConnell J
Sports Med 2012 Jan 1;42(1):51-67. doi: 10.2165/11595680-000000000-00000. PMID: 22149697

Recent clinical studies

Etiology

ARTHROPLASTY IN DYSPLSATIC COXARTHROSIS.
Polulyakh M, Gerasimenko S, Polulyakh D, Kostyuk A, Huzhevskyi I
Georgian Med News 2022 Jul-Aug;(328-329):34-37. PMID: 36318838
Achondroplasia: Really rhizomelic?
Shelmerdine SC, Brittain H, Arthurs OJ, Calder AD
Am J Med Genet A 2016 Aug;170(8):2039-43. Epub 2016 Jun 3 doi: 10.1002/ajmg.a.37776. PMID: 27257098
Shwachman-Diamond syndrome.
Dall'oca C, Bondi M, Merlini M, Cipolli M, Lavini F, Bartolozzi P
Musculoskelet Surg 2012 Aug;96(2):81-8. Epub 2011 Dec 27 doi: 10.1007/s12306-011-0174-z. PMID: 22201042
Blount disease.
Sabharwal S
J Bone Joint Surg Am 2009 Jul;91(7):1758-76. doi: 10.2106/JBJS.H.01348. PMID: 19571101
Brachydactyly.
Temtamy SA, Aglan MS
Orphanet J Rare Dis 2008 Jun 13;3:15. doi: 10.1186/1750-1172-3-15. PMID: 18554391Free PMC Article

Diagnosis

Hypothesis: Symbrachydactyly.
Holmes LB, Nasri HZ
Am J Med Genet A 2022 Nov;188(11):3236-3241. Epub 2022 Sep 8 doi: 10.1002/ajmg.a.62941. PMID: 36073773
Overview of Metatarsalgia.
Charen DA, Markowitz JS, Cheung ZB, Matijakovich DJ, Chan JJ, Vulcano E
Orthopedics 2019 Jan 1;42(1):e138-e143. Epub 2018 Dec 13 doi: 10.3928/01477447-20181206-06. PMID: 30540873
Achondroplasia: Really rhizomelic?
Shelmerdine SC, Brittain H, Arthurs OJ, Calder AD
Am J Med Genet A 2016 Aug;170(8):2039-43. Epub 2016 Jun 3 doi: 10.1002/ajmg.a.37776. PMID: 27257098
Congenital fibular deficiency.
Hamdy RC, Makhdom AM, Saran N, Birch J
J Am Acad Orthop Surg 2014 Apr;22(4):246-55. doi: 10.5435/JAAOS-22-04-246. PMID: 24668354
Brachydactyly.
Temtamy SA, Aglan MS
Orphanet J Rare Dis 2008 Jun 13;3:15. doi: 10.1186/1750-1172-3-15. PMID: 18554391Free PMC Article

Therapy

Has the Threshold for Epiphysiodesis Versus Lengthening Changed in the Era of Magnetically Controlled Nails?
Nichols LRB
J Pediatr Orthop 2021 Jul 1;41(Suppl 1):S24-S32. doi: 10.1097/BPO.0000000000001801. PMID: 34096534
Radial Ray Malformation.
Society for Maternal-Fetal Medicine (SMFM), Gandhi M, Rac MWF, McKinney J
Am J Obstet Gynecol 2019 Dec;221(6):B16-B18. doi: 10.1016/j.ajog.2019.09.024. PMID: 31787159
Percutaneous Pediatric Foot and Ankle Surgery.
Uglow MG
Foot Ankle Clin 2016 Sep;21(3):577-94. Epub 2016 Jun 29 doi: 10.1016/j.fcl.2016.04.005. PMID: 27524707
Shwachman-Diamond syndrome.
Dall'oca C, Bondi M, Merlini M, Cipolli M, Lavini F, Bartolozzi P
Musculoskelet Surg 2012 Aug;96(2):81-8. Epub 2011 Dec 27 doi: 10.1007/s12306-011-0174-z. PMID: 22201042
Lower-limb deficiencies and amputations in children.
Krajbich JI
J Am Acad Orthop Surg 1998 Nov-Dec;6(6):358-67. doi: 10.5435/00124635-199811000-00004. PMID: 9826419

Prognosis

Radiographic analysis of Müller-Weiss disease.
Wong-Chung J, McKenna R, Tucker A, Gibson D, Datta P
Foot Ankle Surg 2021 Jul;27(5):501-509. Epub 2020 Jun 18 doi: 10.1016/j.fas.2020.06.009. PMID: 32600969
Congenital Tibial Deficiency.
Litrenta J, Young M, Birch JG, Oetgen ME
J Am Acad Orthop Surg 2019 Mar 15;27(6):e268-e279. doi: 10.5435/JAAOS-D-16-00838. PMID: 30418269
Scott-Taor syndrome.
Ayyıldız VA, Özgökçe M, Oğul H
Joint Bone Spine 2017 Dec;84(6):739. Epub 2017 Feb 11 doi: 10.1016/j.jbspin.2017.01.007. PMID: 28196777
Brachydactyly.
Temtamy SA, Aglan MS
Orphanet J Rare Dis 2008 Jun 13;3:15. doi: 10.1186/1750-1172-3-15. PMID: 18554391Free PMC Article
Sacrococcygeal dysgenesis association.
Duncan PA, Shapiro LR, Klein RM
Am J Med Genet 1991 Nov 1;41(2):153-61. doi: 10.1002/ajmg.1320410203. PMID: 1785625

Clinical prediction guides

Congenital Tibial Deficiency.
Litrenta J, Young M, Birch JG, Oetgen ME
J Am Acad Orthop Surg 2019 Mar 15;27(6):e268-e279. doi: 10.5435/JAAOS-D-16-00838. PMID: 30418269
Genetics of patella hypoplasia/agenesis.
Vanlerberghe C, Boutry N, Petit F
Clin Genet 2018 Jul;94(1):43-53. Epub 2018 Apr 11 doi: 10.1111/cge.13209. PMID: 29322497
Achondroplasia: Really rhizomelic?
Shelmerdine SC, Brittain H, Arthurs OJ, Calder AD
Am J Med Genet A 2016 Aug;170(8):2039-43. Epub 2016 Jun 3 doi: 10.1002/ajmg.a.37776. PMID: 27257098
Coccygeal pits.
Weprin BE, Oakes WJ
Pediatrics 2000 May;105(5):E69. doi: 10.1542/peds.105.5.e69. PMID: 10799633
Epiphyseal clefts.
Harrison RB, Keats TE
Skeletal Radiol 1980 Feb;5(1):23-7. doi: 10.1007/BF00347094. PMID: 6767277

Recent systematic reviews

Split cord malformation concomitant with spinal teratoma without open spinal dysraphism.
Hazneci J, Bastacı F, Börekci A, Öztürk ÖÇ, İş M, Somay A, Ekşi MŞ, Çelikoğlu E
Childs Nerv Syst 2022 Oct;38(10):1977-1986. Epub 2022 Jun 10 doi: 10.1007/s00381-022-05578-5. PMID: 35687168
Surgical interventions of Freiberg's disease: A systematic review.
Alhadhoud MA, Alsiri NF, Daniels TR, Glazebrook MA
Foot Ankle Surg 2021 Aug;27(6):606-614. Epub 2020 Aug 27 doi: 10.1016/j.fas.2020.08.005. PMID: 32917526
The management of the painful bipartite patella: a systematic review.
McMahon SE, LeRoux JA, Smith TO, Hing CB
Knee Surg Sports Traumatol Arthrosc 2016 Sep;24(9):2798-2805. Epub 2015 Jan 7 doi: 10.1007/s00167-014-3498-z. PMID: 25564195
The etiology of short stature affects the clinical outcome of lower limb lengthening using external fixation. A systematic review of 18 trials involving 547 patients.
Kim SJ, Pierce W, Sabharwal S
Acta Orthop 2014 Apr;85(2):181-6. doi: 10.3109/17453674.2014.899856. PMID: 24650027Free PMC Article
Treatment of dysplasia epiphysealis hemimelica: a systematic review of published reports and a report of seven patients.
Struijs PA, Kerkhoffs GM, Besselaar PP
J Foot Ankle Surg 2012 Sep-Oct;51(5):620-6. Epub 2012 Jul 21 doi: 10.1053/j.jfas.2012.05.008. PMID: 22819617

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