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Abnormal fingernail morphology

MedGen UID:
867411
Concept ID:
C4021782
Anatomical Abnormality
Synonym: Abnormality of the fingernails
 
HPO: HP:0001231

Definition

An abnormality of the fingernails. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormal fingernail morphology

Conditions with this feature

Tooth agenesis, selective, 3
MedGen UID:
410035
Concept ID:
C1970291
Disease or Syndrome
Any tooth agenesis in which the cause of the disease is a mutation in the PAX9 gene.

Professional guidelines

PubMed

Prasasya R, Grotheer KV, Siracusa LD, Bartolomei MS
Hum Mol Genet 2020 Sep 30;29(R1):R107-R116. doi: 10.1093/hmg/ddaa133. PMID: 32592473Free PMC Article
Herrick AL
Nat Rev Rheumatol 2012 Aug;8(8):469-79. Epub 2012 Jul 10 doi: 10.1038/nrrheum.2012.96. PMID: 22782008
Hinds G, Thomas VD
Dermatol Clin 2008 Jan;26(1):59-68, viii. doi: 10.1016/j.det.2007.08.003. PMID: 18023771

Recent clinical studies

Etiology

Smith V, Ickinger C, Hysa E, Snow M, Frech T, Sulli A, Cutolo M
Best Pract Res Clin Rheumatol 2023 Mar;37(1):101849. Epub 2023 Jul 6 doi: 10.1016/j.berh.2023.101849. PMID: 37419757
Fukasawa T, Toyama S, Enomoto A, Yoshizaki-Ogawa A, Norimatsu Y, Tateishi S, Kanda H, Miyagawa K, Sato S, Yoshizaki A
Rheumatology (Oxford) 2023 Jul 5;62(7):2418-2425. doi: 10.1093/rheumatology/keac664. PMID: 36440919
Smith V, Herrick AL, Ingegnoli F, Damjanov N, De Angelis R, Denton CP, Distler O, Espejo K, Foeldvari I, Frech T, Garro B, Gutierrez M, Gyger G, Hachulla E, Hesselstrand R, Iagnocco A, Kayser C, Melsens K, Müller-Ladner U, Paolino S, Pizzorni C, Radic M, Riccieri V, Snow M, Stevens W, Sulli A, van Laar JM, Vonk MC, Vanhaecke A, Cutolo M; EULAR Study Group on Microcirculation in Rheumatic Diseases and the Scleroderma Clinical Trials Consortium Group on Capillaroscopy
Autoimmun Rev 2020 Mar;19(3):102458. Epub 2020 Jan 10 doi: 10.1016/j.autrev.2020.102458. PMID: 31927087
Baglam T, Binnetoglu A, Fatih Topuz M, Baş Ikizoglu N, Ersu R, Turan S, Sarı M
Int J Pediatr Otorhinolaryngol 2017 Apr;95:91-96. Epub 2017 Feb 11 doi: 10.1016/j.ijporl.2017.02.009. PMID: 28576543
Savage SA, Alter BP
Hematol Oncol Clin North Am 2009 Apr;23(2):215-31. doi: 10.1016/j.hoc.2009.01.003. PMID: 19327580Free PMC Article

Diagnosis

Smith V, Ickinger C, Hysa E, Snow M, Frech T, Sulli A, Cutolo M
Best Pract Res Clin Rheumatol 2023 Mar;37(1):101849. Epub 2023 Jul 6 doi: 10.1016/j.berh.2023.101849. PMID: 37419757
Smith V, Herrick AL, Ingegnoli F, Damjanov N, De Angelis R, Denton CP, Distler O, Espejo K, Foeldvari I, Frech T, Garro B, Gutierrez M, Gyger G, Hachulla E, Hesselstrand R, Iagnocco A, Kayser C, Melsens K, Müller-Ladner U, Paolino S, Pizzorni C, Radic M, Riccieri V, Snow M, Stevens W, Sulli A, van Laar JM, Vonk MC, Vanhaecke A, Cutolo M; EULAR Study Group on Microcirculation in Rheumatic Diseases and the Scleroderma Clinical Trials Consortium Group on Capillaroscopy
Autoimmun Rev 2020 Mar;19(3):102458. Epub 2020 Jan 10 doi: 10.1016/j.autrev.2020.102458. PMID: 31927087
van der Sluijs PJ, Jansen S, Vergano SA, Adachi-Fukuda M, Alanay Y, AlKindy A, Baban A, Bayat A, Beck-Wödl S, Berry K, Bijlsma EK, Bok LA, Brouwer AFJ, van der Burgt I, Campeau PM, Canham N, Chrzanowska K, Chu YWY, Chung BHY, Dahan K, De Rademaeker M, Destree A, Dudding-Byth T, Earl R, Elcioglu N, Elias ER, Fagerberg C, Gardham A, Gener B, Gerkes EH, Grasshoff U, van Haeringen A, Heitink KR, Herkert JC, den Hollander NS, Horn D, Hunt D, Kant SG, Kato M, Kayserili H, Kersseboom R, Kilic E, Krajewska-Walasek M, Lammers K, Laulund LW, Lederer D, Lees M, López-González V, Maas S, Mancini GMS, Marcelis C, Martinez F, Maystadt I, McGuire M, McKee S, Mehta S, Metcalfe K, Milunsky J, Mizuno S, Moeschler JB, Netzer C, Ockeloen CW, Oehl-Jaschkowitz B, Okamoto N, Olminkhof SNM, Orellana C, Pasquier L, Pottinger C, Riehmer V, Robertson SP, Roifman M, Rooryck C, Ropers FG, Rosello M, Ruivenkamp CAL, Sagiroglu MS, Sallevelt SCEH, Sanchis Calvo A, Simsek-Kiper PO, Soares G, Solaeche L, Sonmez FM, Splitt M, Steenbeek D, Stegmann APA, Stumpel CTRM, Tanabe S, Uctepe E, Utine GE, Veenstra-Knol HE, Venkateswaran S, Vilain C, Vincent-Delorme C, Vulto-van Silfhout AT, Wheeler P, Wilson GN, Wilson LC, Wollnik B, Kosho T, Wieczorek D, Eichler E, Pfundt R, de Vries BBA, Clayton-Smith J, Santen GWE
Genet Med 2019 Jun;21(6):1295-1307. Epub 2018 Nov 8 doi: 10.1038/s41436-018-0330-z. PMID: 30349098Free PMC Article
Lencastre A, Lamas A, Sá D, Tosti A
Clin Dermatol 2013 Sep-Oct;31(5):587-93. doi: 10.1016/j.clindermatol.2013.06.016. PMID: 24079588
Grinzi P
Aust Fam Physician 2011 Jul;40(7):476-84. PMID: 21743851

Therapy

Reszke R, Szepietowski JC
Expert Opin Drug Saf 2020 Apr;19(4):373-380. Epub 2020 Mar 11 doi: 10.1080/14740338.2020.1736553. PMID: 32129112
Baglam T, Binnetoglu A, Fatih Topuz M, Baş Ikizoglu N, Ersu R, Turan S, Sarı M
Int J Pediatr Otorhinolaryngol 2017 Apr;95:91-96. Epub 2017 Feb 11 doi: 10.1016/j.ijporl.2017.02.009. PMID: 28576543
Khunger N, Kandhari R
Indian J Dermatol Venereol Leprol 2012 May-Jun;78(3):279-89. doi: 10.4103/0378-6323.95442. PMID: 22565427
Haneke E
J Cosmet Dermatol 2006 Mar;5(1):95-100. doi: 10.1111/j.1473-2165.2006.00232.x. PMID: 17173580
Kirkpatrick CH
J Am Acad Dermatol 1994 Sep;31(3 Pt 2):S14-7. doi: 10.1016/s0190-9622(08)81260-1. PMID: 8077500

Prognosis

Smith V, Ickinger C, Hysa E, Snow M, Frech T, Sulli A, Cutolo M
Best Pract Res Clin Rheumatol 2023 Mar;37(1):101849. Epub 2023 Jul 6 doi: 10.1016/j.berh.2023.101849. PMID: 37419757
Fukasawa T, Toyama S, Enomoto A, Yoshizaki-Ogawa A, Norimatsu Y, Tateishi S, Kanda H, Miyagawa K, Sato S, Yoshizaki A
Rheumatology (Oxford) 2023 Jul 5;62(7):2418-2425. doi: 10.1093/rheumatology/keac664. PMID: 36440919
Smith V, Herrick AL, Ingegnoli F, Damjanov N, De Angelis R, Denton CP, Distler O, Espejo K, Foeldvari I, Frech T, Garro B, Gutierrez M, Gyger G, Hachulla E, Hesselstrand R, Iagnocco A, Kayser C, Melsens K, Müller-Ladner U, Paolino S, Pizzorni C, Radic M, Riccieri V, Snow M, Stevens W, Sulli A, van Laar JM, Vonk MC, Vanhaecke A, Cutolo M; EULAR Study Group on Microcirculation in Rheumatic Diseases and the Scleroderma Clinical Trials Consortium Group on Capillaroscopy
Autoimmun Rev 2020 Mar;19(3):102458. Epub 2020 Jan 10 doi: 10.1016/j.autrev.2020.102458. PMID: 31927087
Adya KA, Inamadar AC, Palit A
Int J Dermatol 2017 Jan;56(1):3-17. Epub 2016 Sep 9 doi: 10.1111/ijd.13358. PMID: 27613605
Cutolo M, Sulli A, Smith V
Best Pract Res Clin Rheumatol 2013 Apr;27(2):237-48. doi: 10.1016/j.berh.2013.03.001. PMID: 23731933

Clinical prediction guides

Smith V, Ickinger C, Hysa E, Snow M, Frech T, Sulli A, Cutolo M
Best Pract Res Clin Rheumatol 2023 Mar;37(1):101849. Epub 2023 Jul 6 doi: 10.1016/j.berh.2023.101849. PMID: 37419757
Fukasawa T, Toyama S, Enomoto A, Yoshizaki-Ogawa A, Norimatsu Y, Tateishi S, Kanda H, Miyagawa K, Sato S, Yoshizaki A
Rheumatology (Oxford) 2023 Jul 5;62(7):2418-2425. doi: 10.1093/rheumatology/keac664. PMID: 36440919
Smith V, Herrick AL, Ingegnoli F, Damjanov N, De Angelis R, Denton CP, Distler O, Espejo K, Foeldvari I, Frech T, Garro B, Gutierrez M, Gyger G, Hachulla E, Hesselstrand R, Iagnocco A, Kayser C, Melsens K, Müller-Ladner U, Paolino S, Pizzorni C, Radic M, Riccieri V, Snow M, Stevens W, Sulli A, van Laar JM, Vonk MC, Vanhaecke A, Cutolo M; EULAR Study Group on Microcirculation in Rheumatic Diseases and the Scleroderma Clinical Trials Consortium Group on Capillaroscopy
Autoimmun Rev 2020 Mar;19(3):102458. Epub 2020 Jan 10 doi: 10.1016/j.autrev.2020.102458. PMID: 31927087
van der Sluijs PJ, Jansen S, Vergano SA, Adachi-Fukuda M, Alanay Y, AlKindy A, Baban A, Bayat A, Beck-Wödl S, Berry K, Bijlsma EK, Bok LA, Brouwer AFJ, van der Burgt I, Campeau PM, Canham N, Chrzanowska K, Chu YWY, Chung BHY, Dahan K, De Rademaeker M, Destree A, Dudding-Byth T, Earl R, Elcioglu N, Elias ER, Fagerberg C, Gardham A, Gener B, Gerkes EH, Grasshoff U, van Haeringen A, Heitink KR, Herkert JC, den Hollander NS, Horn D, Hunt D, Kant SG, Kato M, Kayserili H, Kersseboom R, Kilic E, Krajewska-Walasek M, Lammers K, Laulund LW, Lederer D, Lees M, López-González V, Maas S, Mancini GMS, Marcelis C, Martinez F, Maystadt I, McGuire M, McKee S, Mehta S, Metcalfe K, Milunsky J, Mizuno S, Moeschler JB, Netzer C, Ockeloen CW, Oehl-Jaschkowitz B, Okamoto N, Olminkhof SNM, Orellana C, Pasquier L, Pottinger C, Riehmer V, Robertson SP, Roifman M, Rooryck C, Ropers FG, Rosello M, Ruivenkamp CAL, Sagiroglu MS, Sallevelt SCEH, Sanchis Calvo A, Simsek-Kiper PO, Soares G, Solaeche L, Sonmez FM, Splitt M, Steenbeek D, Stegmann APA, Stumpel CTRM, Tanabe S, Uctepe E, Utine GE, Veenstra-Knol HE, Venkateswaran S, Vilain C, Vincent-Delorme C, Vulto-van Silfhout AT, Wheeler P, Wilson GN, Wilson LC, Wollnik B, Kosho T, Wieczorek D, Eichler E, Pfundt R, de Vries BBA, Clayton-Smith J, Santen GWE
Genet Med 2019 Jun;21(6):1295-1307. Epub 2018 Nov 8 doi: 10.1038/s41436-018-0330-z. PMID: 30349098Free PMC Article
Lencastre A, Lamas A, Sá D, Tosti A
Clin Dermatol 2013 Sep-Oct;31(5):587-93. doi: 10.1016/j.clindermatol.2013.06.016. PMID: 24079588

Recent systematic reviews

Piette Y, Reynaert V, Vanhaecke A, Bonroy C, Gutermuth J, Sulli A, Cutolo M, Smith V
Autoimmun Rev 2022 Jun;21(6):103087. Epub 2022 Apr 12 doi: 10.1016/j.autrev.2022.103087. PMID: 35421608
Schonenberg-Meinema D, Melsens K, Nassar-Sheikh Rashid A, Cutolo M, Kuijpers TW, van den Berg JM, Smith V
Clin Exp Rheumatol 2020 Mar-Apr;38(2):350-354. Epub 2019 Dec 18 doi: 10.55563/clinexprheumatol/azl2bj. PMID: 31858964
Tatiane A, Slape D, Lawless R, Frew JW
Clin Exp Dermatol 2019 Aug;44(6):606-612. Epub 2019 May 10 doi: 10.1111/ced.13980. PMID: 31074523
Cutolo M, Melsens K, Wijnant S, Ingegnoli F, Thevissen K, De Keyser F, Decuman S, Müller-Ladner U, Piette Y, Riccieri V, Ughi N, Vandecasteele E, Vanhaecke A, Smith V
Autoimmun Rev 2018 Apr;17(4):344-352. Epub 2018 Feb 8 doi: 10.1016/j.autrev.2017.11.025. PMID: 29427827
Brauer CA, Lee BM, Bae DS, Waters PM, Kocher MS
J Pediatr Orthop 2007 Mar;27(2):181-6. doi: 10.1097/bpo.0b013e3180316cf1. PMID: 17314643

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