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Primary intraosseous squamous cell carcinoma

MedGen UID:
313618
•Concept ID:
C1709663
•
Neoplastic Process
Synonyms: PIOSCC; Primary Intraosseous Carcinoma, NOS; Primary Intraosseous Carcinoma, Not Otherwise Specified; Primary Intraosseous Squamous Cell Carcinoma; primary intraosseous squamous cell carcinoma
 
Monarch Initiative: MONDO:0006385

Definition

A squamous cell carcinoma that arises centrally from the jaw. It derives from odontogenic epithelial remnants. It includes solid type squamous cell carcinoma, squamous cell carcinoma that arises from an odontogenic cyst, and squamous cell carcinoma that derives from a keratocystic odontogenic tumor. [from NCI]

Professional guidelines

PubMed

Primary intraosseous carcinoma: review of the literature and diagnostic criteria.
Suei Y, Tanimoto K, Taguchi A, Wada T
J Oral Maxillofac Surg 1994 Jun;52(6):580-3. doi: 10.1016/0278-2391(94)90094-9. PMID: 8189294

Recent clinical studies

Etiology

Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: case series and literature review.
Ye P, Wei T, Gao Y, Zhang W, Peng X
Med Oral Patol Oral Cir Bucal 2021 Jan 1;26(1):e49-e55. doi: 10.4317/medoral.23947. PMID: 33037806Free PMC Article
Primary intraosseous squamous cell carcinoma of the mandible: locoregional control and survival is significantly reduced if the tumour is more than 4cm in size.
Shen Q, Chen Y, Gokavarapu S, Cao W, Ji T
Br J Oral Maxillofac Surg 2018 Jan;56(1):48-53. Epub 2017 Dec 8 doi: 10.1016/j.bjoms.2017.11.007. PMID: 29229291
Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma (PIOSCC): A Retrospective Review.
Wenguang X, Hao S, Xiaofeng Q, Zhiyong W, Yufeng W, Qingang H, Wei H
PLoS One 2016;11(4):e0153646. Epub 2016 Apr 13 doi: 10.1371/journal.pone.0153646. PMID: 27074366Free PMC Article
Primary Intraosseous Squamous Cell Carcinoma of the Jaws: 6 New Cases, Experience, and Literature Comparison.
Boni P, Sozzi D, Novelli G, Pagni F, Valente G, Bozzetti A
J Oral Maxillofac Surg 2016 Mar;74(3):541-6. Epub 2015 Sep 21 doi: 10.1016/j.joms.2015.09.009. PMID: 26433039
Malignant epithelial odontogenic tumors.
Eversole LR
Semin Diagn Pathol 1999 Nov;16(4):317-24. PMID: 10587275

Diagnosis

Primary Intraosseous Squamous Cell Carcinoma of the Mandible Mimicking Inflammation on FDG PET/CT.
Fan Q, Wang R, Tian R, Su M
Clin Nucl Med 2022 Feb 1;47(2):156-158. doi: 10.1097/RLU.0000000000003769. PMID: 34132676
Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update.
de Morais EF, Carlan LM, de Farias Morais HG, Pinheiro JC, Martins HDD, Barboza CAG, de Almeida Freitas R
Head Neck Pathol 2021 Jun;15(2):608-616. Epub 2020 Oct 12 doi: 10.1007/s12105-020-01234-z. PMID: 33044723Free PMC Article
Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma (PIOSCC): A Retrospective Review.
Wenguang X, Hao S, Xiaofeng Q, Zhiyong W, Yufeng W, Qingang H, Wei H
PLoS One 2016;11(4):e0153646. Epub 2016 Apr 13 doi: 10.1371/journal.pone.0153646. PMID: 27074366Free PMC Article
Primary intraosseous squamous cell carcinoma arising in odontogenic cysts: an insight in pathogenesis.
Jain M, Mittal S, Gupta DK
J Oral Maxillofac Surg 2013 Jan;71(1):e7-14. Epub 2012 Oct 23 doi: 10.1016/j.joms.2012.08.031. PMID: 23092745
Malignant epithelial odontogenic tumors.
Eversole LR
Semin Diagn Pathol 1999 Nov;16(4):317-24. PMID: 10587275

Prognosis

Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update.
de Morais EF, Carlan LM, de Farias Morais HG, Pinheiro JC, Martins HDD, Barboza CAG, de Almeida Freitas R
Head Neck Pathol 2021 Jun;15(2):608-616. Epub 2020 Oct 12 doi: 10.1007/s12105-020-01234-z. PMID: 33044723Free PMC Article
Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: case series and literature review.
Ye P, Wei T, Gao Y, Zhang W, Peng X
Med Oral Patol Oral Cir Bucal 2021 Jan 1;26(1):e49-e55. doi: 10.4317/medoral.23947. PMID: 33037806Free PMC Article
Primary intraosseous squamous cell carcinoma of the mandible: locoregional control and survival is significantly reduced if the tumour is more than 4cm in size.
Shen Q, Chen Y, Gokavarapu S, Cao W, Ji T
Br J Oral Maxillofac Surg 2018 Jan;56(1):48-53. Epub 2017 Dec 8 doi: 10.1016/j.bjoms.2017.11.007. PMID: 29229291
Clinicopathological Study of Primary Intraosseous Squamous Cell Carcinoma of the Jaw and a Review of the Literature.
Naruse T, Yanamoto S, Sakamoto Y, Ikeda T, Yamada SI, Umeda M
J Oral Maxillofac Surg 2016 Dec;74(12):2420-2427. Epub 2016 May 18 doi: 10.1016/j.joms.2016.05.006. PMID: 27280805
Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma (PIOSCC): A Retrospective Review.
Wenguang X, Hao S, Xiaofeng Q, Zhiyong W, Yufeng W, Qingang H, Wei H
PLoS One 2016;11(4):e0153646. Epub 2016 Apr 13 doi: 10.1371/journal.pone.0153646. PMID: 27074366Free PMC Article

Clinical prediction guides

Primary Intraosseous Squamous Cell Carcinoma of the Jaws: 6 New Cases, Experience, and Literature Comparison.
Boni P, Sozzi D, Novelli G, Pagni F, Valente G, Bozzetti A
J Oral Maxillofac Surg 2016 Mar;74(3):541-6. Epub 2015 Sep 21 doi: 10.1016/j.joms.2015.09.009. PMID: 26433039
Primary intraosseous squamous cell carcinoma arising in odontogenic cysts: an insight in pathogenesis.
Jain M, Mittal S, Gupta DK
J Oral Maxillofac Surg 2013 Jan;71(1):e7-14. Epub 2012 Oct 23 doi: 10.1016/j.joms.2012.08.031. PMID: 23092745

Recent systematic reviews

Primary Intraosseous Squamous Cell Carcinoma Involving the Jaw Bones: A Systematic Review and Update.
de Morais EF, Carlan LM, de Farias Morais HG, Pinheiro JC, Martins HDD, Barboza CAG, de Almeida Freitas R
Head Neck Pathol 2021 Jun;15(2):608-616. Epub 2020 Oct 12 doi: 10.1007/s12105-020-01234-z. PMID: 33044723Free PMC Article
Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: case series and literature review.
Ye P, Wei T, Gao Y, Zhang W, Peng X
Med Oral Patol Oral Cir Bucal 2021 Jan 1;26(1):e49-e55. doi: 10.4317/medoral.23947. PMID: 33037806Free PMC Article

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