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Locally Recurrent Head and Neck Squamous Cell Carcinoma

MedGen UID:
1784906
•Concept ID:
C5447371
•
Neoplastic Process

Definition

The reemergence of head and neck squamous cell carcinoma after a period of remission, at or adjacent to the site of the original tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Recurrent Head and Neck Squamous Cell Carcinoma

Professional guidelines

PubMed

Pembrolizumab in the first-line treatment of advanced head and neck cancer.
de Sousa LG, Ferrarotto R
Expert Rev Anticancer Ther 2021 Dec;21(12):1321-1331. Epub 2021 Nov 2 doi: 10.1080/14737140.2021.1996228. PMID: 34689660
Target delineation for postoperative treatment of head and neck cancer.
Evans M, Beasley M
Oral Oncol 2018 Nov;86:288-295. Epub 2018 Oct 12 doi: 10.1016/j.oraloncology.2018.08.011. PMID: 30409314
Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment.
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Recent clinical studies

Etiology

Boron neutron capture therapy for locally recurrent head and neck squamous cell carcinoma: An analysis of dose response and survival.
Koivunoro H, Kankaanranta L, Seppälä T, Haapaniemi A, Mäkitie A, Joensuu H
Radiother Oncol 2019 Aug;137:153-158. Epub 2019 May 17 doi: 10.1016/j.radonc.2019.04.033. PMID: 31108276
Elective lymphadenectomy during salvage for locally recurrent head and neck squamous cell carcinoma after radiation.
Prendes BL, Aubin-Pouliot A, Egbert N, Ryan WR
Otolaryngol Head Neck Surg 2014 Sep;151(3):462-7. Epub 2014 Jun 3 doi: 10.1177/0194599814537444. PMID: 24894423
Concurrent cetuximab with stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: a single institution matched case-control study.
Heron DE, Rwigema JC, Gibson MK, Burton SA, Quinn AE, Ferris RL
Am J Clin Oncol 2011 Apr;34(2):165-72. doi: 10.1097/COC.0b013e3181dbb73e. PMID: 20686406
Elective neck dissection during salvage surgery for locally recurrent head and neck squamous cell carcinoma after radiotherapy with elective nodal irradiation.
Dagan R, Morris CG, Kirwan JM, Werning JW, Vaysberg M, Amdur RJ, Mendenhall WM
Laryngoscope 2010 May;120(5):945-52. doi: 10.1002/lary.20854. PMID: 20422688
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.
van Houten VM, Leemans CR, Kummer JA, Dijkstra J, Kuik DJ, van den Brekel MW, Snow GB, Brakenhoff RH
Clin Cancer Res 2004 Jun 1;10(11):3614-20. doi: 10.1158/1078-0432.CCR-03-0631. PMID: 15173067

Diagnosis

Diagnosis of locally recurrent head and neck squamous cell carcinoma in the Nordic HNC centers and feasibility of the Odense-Birmingham definition.
Rohde M, Eriksen JG, Pareek M, Bratland Å, Mäkitie A, Hammarstedt-Nordenvall L, Wessel I, Lybeck JS, Mäenpää H, Gebre-Medhin M, Godballe C
Acta Oncol 2023 Sep;62(9):1102-1105. Epub 2023 Aug 21 doi: 10.1080/0284186X.2023.2245550. PMID: 37602835
Definition of locally recurrent head and neck squamous cell carcinoma: a systematic review and proposal for the Odense-Birmingham definition.
Rohde M, Rosenberg T, Pareek M, Nankivell P, Sharma N, Mehanna H, Godballe C
Eur Arch Otorhinolaryngol 2020 Jun;277(6):1593-1599. Epub 2020 Apr 7 doi: 10.1007/s00405-020-05953-5. PMID: 32266461
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.
van Houten VM, Leemans CR, Kummer JA, Dijkstra J, Kuik DJ, van den Brekel MW, Snow GB, Brakenhoff RH
Clin Cancer Res 2004 Jun 1;10(11):3614-20. doi: 10.1158/1078-0432.CCR-03-0631. PMID: 15173067

Therapy

Concurrent cetuximab with stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: a single institution matched case-control study.
Heron DE, Rwigema JC, Gibson MK, Burton SA, Quinn AE, Ferris RL
Am J Clin Oncol 2011 Apr;34(2):165-72. doi: 10.1097/COC.0b013e3181dbb73e. PMID: 20686406

Prognosis

Boron neutron capture therapy: moving towards targeted therapy for locally recurrent head and neck squamous cell carcinoma.
Sun Y
Mil Med Res 2019 Oct 25;6(1):32. doi: 10.1186/s40779-019-0224-7. PMID: 31651361Free PMC Article
Boron neutron capture therapy for locally recurrent head and neck squamous cell carcinoma: An analysis of dose response and survival.
Koivunoro H, Kankaanranta L, Seppälä T, Haapaniemi A, Mäkitie A, Joensuu H
Radiother Oncol 2019 Aug;137:153-158. Epub 2019 May 17 doi: 10.1016/j.radonc.2019.04.033. PMID: 31108276
Concurrent cetuximab with stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: a single institution matched case-control study.
Heron DE, Rwigema JC, Gibson MK, Burton SA, Quinn AE, Ferris RL
Am J Clin Oncol 2011 Apr;34(2):165-72. doi: 10.1097/COC.0b013e3181dbb73e. PMID: 20686406
Elective neck dissection during salvage surgery for locally recurrent head and neck squamous cell carcinoma after radiotherapy with elective nodal irradiation.
Dagan R, Morris CG, Kirwan JM, Werning JW, Vaysberg M, Amdur RJ, Mendenhall WM
Laryngoscope 2010 May;120(5):945-52. doi: 10.1002/lary.20854. PMID: 20422688
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.
van Houten VM, Leemans CR, Kummer JA, Dijkstra J, Kuik DJ, van den Brekel MW, Snow GB, Brakenhoff RH
Clin Cancer Res 2004 Jun 1;10(11):3614-20. doi: 10.1158/1078-0432.CCR-03-0631. PMID: 15173067

Clinical prediction guides

Boron neutron capture therapy for locally recurrent head and neck squamous cell carcinoma: An analysis of dose response and survival.
Koivunoro H, Kankaanranta L, Seppälä T, Haapaniemi A, Mäkitie A, Joensuu H
Radiother Oncol 2019 Aug;137:153-158. Epub 2019 May 17 doi: 10.1016/j.radonc.2019.04.033. PMID: 31108276
Elective lymphadenectomy during salvage for locally recurrent head and neck squamous cell carcinoma after radiation.
Prendes BL, Aubin-Pouliot A, Egbert N, Ryan WR
Otolaryngol Head Neck Surg 2014 Sep;151(3):462-7. Epub 2014 Jun 3 doi: 10.1177/0194599814537444. PMID: 24894423
Concurrent cetuximab with stereotactic body radiotherapy for recurrent squamous cell carcinoma of the head and neck: a single institution matched case-control study.
Heron DE, Rwigema JC, Gibson MK, Burton SA, Quinn AE, Ferris RL
Am J Clin Oncol 2011 Apr;34(2):165-72. doi: 10.1097/COC.0b013e3181dbb73e. PMID: 20686406
Elective neck dissection during salvage surgery for locally recurrent head and neck squamous cell carcinoma after radiotherapy with elective nodal irradiation.
Dagan R, Morris CG, Kirwan JM, Werning JW, Vaysberg M, Amdur RJ, Mendenhall WM
Laryngoscope 2010 May;120(5):945-52. doi: 10.1002/lary.20854. PMID: 20422688
Molecular diagnosis of surgical margins and local recurrence in head and neck cancer patients: a prospective study.
van Houten VM, Leemans CR, Kummer JA, Dijkstra J, Kuik DJ, van den Brekel MW, Snow GB, Brakenhoff RH
Clin Cancer Res 2004 Jun 1;10(11):3614-20. doi: 10.1158/1078-0432.CCR-03-0631. PMID: 15173067

Recent systematic reviews

Definition of locally recurrent head and neck squamous cell carcinoma: a systematic review and proposal for the Odense-Birmingham definition.
Rohde M, Rosenberg T, Pareek M, Nankivell P, Sharma N, Mehanna H, Godballe C
Eur Arch Otorhinolaryngol 2020 Jun;277(6):1593-1599. Epub 2020 Apr 7 doi: 10.1007/s00405-020-05953-5. PMID: 32266461

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