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Unresectable Salivary Gland Squamous Cell Carcinoma

MedGen UID:
1771591
•Concept ID:
C5419764
•
Neoplastic Process

Definition

Salivary gland squamous cell carcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Salivary Gland Squamous Cell Carcinoma

Professional guidelines

PubMed

Radiotherapy in the management of rare gastrointestinal cancers: A systematic review.
Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390

Recent clinical studies

Etiology

Curative high-dose reirradiation for patients with recurrent head and neck adenoid cystic carcinomas: outcomes and analysis of patterns of failure.
Mahé M, Beddok A, Goudjil F, Ala Eddine C, Bolle S, Champion L, Feuvret L, Herman P, Zefkili S, Choussy O, Le Tourneau C, Dendale R, Buvat I, Sauvaget E, Créhange G, Calugaru V
Int J Radiat Biol 2024;100(1):79-86. Epub 2023 Aug 21 doi: 10.1080/09553002.2023.2242934. PMID: 37526368
A rationale for chemoradiation (vs radiotherapy) in salivary gland cancers? On behalf of the REFCOR (French rare head and neck cancer network).
Cerda T, Sun XS, Vignot S, Marcy PY, Baujat B, Baglin AC, Ali AM, Testelin S, Reyt E, Janot F, Thariat J
Crit Rev Oncol Hematol 2014 Aug;91(2):142-58. Epub 2014 Feb 16 doi: 10.1016/j.critrevonc.2014.02.002. PMID: 24636481
Phase I trial of concurrent hyperfractionated split course radiotherapy (HFx RT), cisplatin (cDDP), and paclitaxel in patients with recurrent, previously irradiated, or treatment-naïve locally advanced upper aerodigestive malignancy.
Langer CJ, Duffy K, Horwitz EM, Litwin S, Rosvold E, Schol J, Keenan E, Nicolaou N, Friedman CD, Ridge JA
Cancer Invest 2006 Mar;24(2):164-73. doi: 10.1080/07357900500524421. PMID: 16537186
Photon irradiation of unresectable carcinomas of salivary glands.
Wang CC, Goodman M
Int J Radiat Oncol Biol Phys 1991 Aug;21(3):569-76. doi: 10.1016/0360-3016(91)90672-q. PMID: 1651301
Neutron vs photon irradiation of inoperable salivary gland tumors: results of an RTOG-MRC Cooperative Randomized Study.
Griffin TW, Pajak TF, Laramore GE, Duncan W, Richter MP, Hendrickson FR, Maor MH
Int J Radiat Oncol Biol Phys 1988 Nov;15(5):1085-90. doi: 10.1016/0360-3016(88)90188-5. PMID: 2846479

Diagnosis

Chemotherapy for salivary gland cancer.
Kaplan MJ, Johns ME, Cantrell RW
Otolaryngol Head Neck Surg 1986 Sep;95(2):165-70. doi: 10.1177/019459988609500206. PMID: 3035459

Therapy

Near-infrared photoimmunotherapy for salivary duct carcinoma.
Makino T, Sato Y, Uraguchi K, Naoi Y, Fukuda Y, Ando M
Auris Nasus Larynx 2024 Apr;51(2):323-327. Epub 2023 Sep 27 doi: 10.1016/j.anl.2023.09.006. PMID: 37775468
Curative high-dose reirradiation for patients with recurrent head and neck adenoid cystic carcinomas: outcomes and analysis of patterns of failure.
Mahé M, Beddok A, Goudjil F, Ala Eddine C, Bolle S, Champion L, Feuvret L, Herman P, Zefkili S, Choussy O, Le Tourneau C, Dendale R, Buvat I, Sauvaget E, Créhange G, Calugaru V
Int J Radiat Biol 2024;100(1):79-86. Epub 2023 Aug 21 doi: 10.1080/09553002.2023.2242934. PMID: 37526368
A rationale for chemoradiation (vs radiotherapy) in salivary gland cancers? On behalf of the REFCOR (French rare head and neck cancer network).
Cerda T, Sun XS, Vignot S, Marcy PY, Baujat B, Baglin AC, Ali AM, Testelin S, Reyt E, Janot F, Thariat J
Crit Rev Oncol Hematol 2014 Aug;91(2):142-58. Epub 2014 Feb 16 doi: 10.1016/j.critrevonc.2014.02.002. PMID: 24636481
Stage 4 squamous cell carcinoma of the tongue in a child: complete response to chemoradiotherapy.
Soni S, Radel E, Smith RV, Edelman M, Sattenberg R, Wadler S, Beitler JJ
J Pediatr Hematol Oncol 2001 Dec;23(9):612-5. doi: 10.1097/00043426-200112000-00012. PMID: 11902307
Chemotherapy for salivary gland cancer.
Kaplan MJ, Johns ME, Cantrell RW
Otolaryngol Head Neck Surg 1986 Sep;95(2):165-70. doi: 10.1177/019459988609500206. PMID: 3035459

Prognosis

Curative high-dose reirradiation for patients with recurrent head and neck adenoid cystic carcinomas: outcomes and analysis of patterns of failure.
Mahé M, Beddok A, Goudjil F, Ala Eddine C, Bolle S, Champion L, Feuvret L, Herman P, Zefkili S, Choussy O, Le Tourneau C, Dendale R, Buvat I, Sauvaget E, Créhange G, Calugaru V
Int J Radiat Biol 2024;100(1):79-86. Epub 2023 Aug 21 doi: 10.1080/09553002.2023.2242934. PMID: 37526368
A rationale for chemoradiation (vs radiotherapy) in salivary gland cancers? On behalf of the REFCOR (French rare head and neck cancer network).
Cerda T, Sun XS, Vignot S, Marcy PY, Baujat B, Baglin AC, Ali AM, Testelin S, Reyt E, Janot F, Thariat J
Crit Rev Oncol Hematol 2014 Aug;91(2):142-58. Epub 2014 Feb 16 doi: 10.1016/j.critrevonc.2014.02.002. PMID: 24636481
Phase I trial of concurrent hyperfractionated split course radiotherapy (HFx RT), cisplatin (cDDP), and paclitaxel in patients with recurrent, previously irradiated, or treatment-naïve locally advanced upper aerodigestive malignancy.
Langer CJ, Duffy K, Horwitz EM, Litwin S, Rosvold E, Schol J, Keenan E, Nicolaou N, Friedman CD, Ridge JA
Cancer Invest 2006 Mar;24(2):164-73. doi: 10.1080/07357900500524421. PMID: 16537186
Photon irradiation of unresectable carcinomas of salivary glands.
Wang CC, Goodman M
Int J Radiat Oncol Biol Phys 1991 Aug;21(3):569-76. doi: 10.1016/0360-3016(91)90672-q. PMID: 1651301
Neutron vs photon irradiation of inoperable salivary gland tumors: results of an RTOG-MRC Cooperative Randomized Study.
Griffin TW, Pajak TF, Laramore GE, Duncan W, Richter MP, Hendrickson FR, Maor MH
Int J Radiat Oncol Biol Phys 1988 Nov;15(5):1085-90. doi: 10.1016/0360-3016(88)90188-5. PMID: 2846479

Clinical prediction guides

Near-infrared photoimmunotherapy for salivary duct carcinoma.
Makino T, Sato Y, Uraguchi K, Naoi Y, Fukuda Y, Ando M
Auris Nasus Larynx 2024 Apr;51(2):323-327. Epub 2023 Sep 27 doi: 10.1016/j.anl.2023.09.006. PMID: 37775468
The role of radiotherapy in the treatment of malignant tumors of the salivary glands.
Reinfuss M, Korzeniowski S
Tumori 1980 Aug 31;66(4):467-74. doi: 10.1177/030089168006600408. PMID: 7414711

Recent systematic reviews

Radiotherapy in the management of rare gastrointestinal cancers: A systematic review.
Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390

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