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Unresectable Paranasal Sinus Squamous Cell Carcinoma

MedGen UID:
1764557
•Concept ID:
C5419761
•
Neoplastic Process

Definition

Paranasal sinus squamous cell carcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Paranasal Sinus Squamous Cell Carcinoma

Professional guidelines

PubMed

Proton beam therapy in multimodal treatment for locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus.
Saito T, Nakayama M, Ohnishi K, Tanaka S, Nakamura M, Murakami M, Matsumoto S, Baba K, Fujii K, Mizumoto M, Tabuchi K, Sakurai H
Radiat Oncol 2023 Jun 29;18(1):106. doi: 10.1186/s13014-023-02296-3. PMID: 37386495Free PMC Article
Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.
Chopra S, Kamdar DP, Cohen DS, Heilbrun LK, Smith D, Kim H, Lin HS, Jacobs JR, Yoo G
Laryngoscope 2017 Apr;127(4):855-861. Epub 2016 Nov 15 doi: 10.1002/lary.26228. PMID: 27859278Free PMC Article
Differential diagnosis and treatment options in paranasal sinus cancers.
Myers LL, Oxford LE
Surg Oncol Clin N Am 2004 Jan;13(1):167-86. doi: 10.1016/S1055-3207(03)00115-7. PMID: 15062368

Recent clinical studies

Etiology

Proton beam therapy in multimodal treatment for locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus.
Saito T, Nakayama M, Ohnishi K, Tanaka S, Nakamura M, Murakami M, Matsumoto S, Baba K, Fujii K, Mizumoto M, Tabuchi K, Sakurai H
Radiat Oncol 2023 Jun 29;18(1):106. doi: 10.1186/s13014-023-02296-3. PMID: 37386495Free PMC Article
Outcomes of Patients With Sinonasal Squamous Cell Carcinoma Treated With Particle Therapy Using Protons or Carbon Ions.
Toyomasu Y, Demizu Y, Matsuo Y, Sulaiman NS, Mima M, Nagano F, Terashima K, Tokumaru S, Hayakawa T, Daimon T, Fuwa N, Sakuma H, Nomoto Y, Okimoto T
Int J Radiat Oncol Biol Phys 2018 Aug 1;101(5):1096-1103. Epub 2018 Apr 22 doi: 10.1016/j.ijrobp.2018.04.041. PMID: 29859787
Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.
Chopra S, Kamdar DP, Cohen DS, Heilbrun LK, Smith D, Kim H, Lin HS, Jacobs JR, Yoo G
Laryngoscope 2017 Apr;127(4):855-861. Epub 2016 Nov 15 doi: 10.1002/lary.26228. PMID: 27859278Free PMC Article
Proton beam therapy for unresectable malignancies of the nasal cavity and paranasal sinuses.
Zenda S, Kohno R, Kawashima M, Arahira S, Nishio T, Tahara M, Hayashi R, Kishimoto S, Ogino T
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1473-8. Epub 2010 Oct 18 doi: 10.1016/j.ijrobp.2010.08.009. PMID: 20961697
Cell carcinoma of the paranasal sinuses and skull base.
McKay SP, Shibuya TY, Armstrong WB, Wong HS, Panossian AM, Ager J, Mathog RH
Am J Otolaryngol 2007 Sep-Oct;28(5):294-301. doi: 10.1016/j.amjoto.2006.09.007. PMID: 17826529

Diagnosis

Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.
Chopra S, Kamdar DP, Cohen DS, Heilbrun LK, Smith D, Kim H, Lin HS, Jacobs JR, Yoo G
Laryngoscope 2017 Apr;127(4):855-861. Epub 2016 Nov 15 doi: 10.1002/lary.26228. PMID: 27859278Free PMC Article
Potential of helical tomotherapy to reduce dose to the ocular structures for patients treated for unresectable sinonasal cancer.
Chen AM, Sreeraman R, Mathai M, Vijayakumar S, Purdy JA
Am J Clin Oncol 2010 Dec;33(6):595-8. doi: 10.1097/COC.0b013e3181c44535. PMID: 20142725
Differential diagnosis and treatment options in paranasal sinus cancers.
Myers LL, Oxford LE
Surg Oncol Clin N Am 2004 Jan;13(1):167-86. doi: 10.1016/S1055-3207(03)00115-7. PMID: 15062368

Therapy

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL
J Immunother Cancer 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5. PMID: 31307547Free PMC Article
Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.
Chopra S, Kamdar DP, Cohen DS, Heilbrun LK, Smith D, Kim H, Lin HS, Jacobs JR, Yoo G
Laryngoscope 2017 Apr;127(4):855-861. Epub 2016 Nov 15 doi: 10.1002/lary.26228. PMID: 27859278Free PMC Article
Proton beam therapy for unresectable malignancies of the nasal cavity and paranasal sinuses.
Zenda S, Kohno R, Kawashima M, Arahira S, Nishio T, Tahara M, Hayashi R, Kishimoto S, Ogino T
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1473-8. Epub 2010 Oct 18 doi: 10.1016/j.ijrobp.2010.08.009. PMID: 20961697
Differential diagnosis and treatment options in paranasal sinus cancers.
Myers LL, Oxford LE
Surg Oncol Clin N Am 2004 Jan;13(1):167-86. doi: 10.1016/S1055-3207(03)00115-7. PMID: 15062368
Management of inverted papilloma of the nasal cavity and paranasal sinuses: importance of radiation therapy.
Hug EB, Wang CC, Montgomery WW, Goodman ML
Int J Radiat Oncol Biol Phys 1993 Apr 30;26(1):67-72. doi: 10.1016/0360-3016(93)90174-t. PMID: 8482632

Prognosis

Proton beam therapy in multimodal treatment for locally advanced squamous cell carcinoma of the nasal cavity and paranasal sinus.
Saito T, Nakayama M, Ohnishi K, Tanaka S, Nakamura M, Murakami M, Matsumoto S, Baba K, Fujii K, Mizumoto M, Tabuchi K, Sakurai H
Radiat Oncol 2023 Jun 29;18(1):106. doi: 10.1186/s13014-023-02296-3. PMID: 37386495Free PMC Article
Outcomes of Patients With Sinonasal Squamous Cell Carcinoma Treated With Particle Therapy Using Protons or Carbon Ions.
Toyomasu Y, Demizu Y, Matsuo Y, Sulaiman NS, Mima M, Nagano F, Terashima K, Tokumaru S, Hayakawa T, Daimon T, Fuwa N, Sakuma H, Nomoto Y, Okimoto T
Int J Radiat Oncol Biol Phys 2018 Aug 1;101(5):1096-1103. Epub 2018 Apr 22 doi: 10.1016/j.ijrobp.2018.04.041. PMID: 29859787
Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.
Chopra S, Kamdar DP, Cohen DS, Heilbrun LK, Smith D, Kim H, Lin HS, Jacobs JR, Yoo G
Laryngoscope 2017 Apr;127(4):855-861. Epub 2016 Nov 15 doi: 10.1002/lary.26228. PMID: 27859278Free PMC Article
Cell carcinoma of the paranasal sinuses and skull base.
McKay SP, Shibuya TY, Armstrong WB, Wong HS, Panossian AM, Ager J, Mathog RH
Am J Otolaryngol 2007 Sep-Oct;28(5):294-301. doi: 10.1016/j.amjoto.2006.09.007. PMID: 17826529
Differential diagnosis and treatment options in paranasal sinus cancers.
Myers LL, Oxford LE
Surg Oncol Clin N Am 2004 Jan;13(1):167-86. doi: 10.1016/S1055-3207(03)00115-7. PMID: 15062368

Clinical prediction guides

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen EEW, Bell RB, Bifulco CB, Burtness B, Gillison ML, Harrington KJ, Le QT, Lee NY, Leidner R, Lewis RL, Licitra L, Mehanna H, Mell LK, Raben A, Sikora AG, Uppaluri R, Whitworth F, Zandberg DP, Ferris RL
J Immunother Cancer 2019 Jul 15;7(1):184. doi: 10.1186/s40425-019-0662-5. PMID: 31307547Free PMC Article
Outcomes of nonsurgical management of locally advanced carcinomas of the sinonasal cavity.
Chopra S, Kamdar DP, Cohen DS, Heilbrun LK, Smith D, Kim H, Lin HS, Jacobs JR, Yoo G
Laryngoscope 2017 Apr;127(4):855-861. Epub 2016 Nov 15 doi: 10.1002/lary.26228. PMID: 27859278Free PMC Article
Proton beam therapy for unresectable malignancies of the nasal cavity and paranasal sinuses.
Zenda S, Kohno R, Kawashima M, Arahira S, Nishio T, Tahara M, Hayashi R, Kishimoto S, Ogino T
Int J Radiat Oncol Biol Phys 2011 Dec 1;81(5):1473-8. Epub 2010 Oct 18 doi: 10.1016/j.ijrobp.2010.08.009. PMID: 20961697
Cell carcinoma of the paranasal sinuses and skull base.
McKay SP, Shibuya TY, Armstrong WB, Wong HS, Panossian AM, Ager J, Mathog RH
Am J Otolaryngol 2007 Sep-Oct;28(5):294-301. doi: 10.1016/j.amjoto.2006.09.007. PMID: 17826529
Paranasal sinus malignancies: an 18-year single institution experience.
Myers LL, Nussenbaum B, Bradford CR, Teknos TN, Esclamado RM, Wolf GT
Laryngoscope 2002 Nov;112(11):1964-9. doi: 10.1097/00005537-200211000-00010. PMID: 12439163

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