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Locally Advanced Laryngeal Squamous Cell Carcinoma

MedGen UID:
1712205
•Concept ID:
C5237210
•
Neoplastic Process

Definition

Laryngeal squamous cell carcinoma that has spread from its original site of growth to nearby tissues or lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLocally Advanced Laryngeal Squamous Cell Carcinoma

Professional guidelines

PubMed

Pembrolizumab in the first-line treatment of advanced head and neck cancer.
de Sousa LG, Ferrarotto R
Expert Rev Anticancer Ther 2021 Dec;21(12):1321-1331. Epub 2021 Nov 2 doi: 10.1080/14737140.2021.1996228. PMID: 34689660
Guidelines of care for the management of cutaneous squamous cell carcinoma.
Work Group; Invited Reviewers, Kim JYS, Kozlow JH, Mittal B, Moyer J, Olenecki T, Rodgers P
J Am Acad Dermatol 2018 Mar;78(3):560-578. Epub 2018 Jan 10 doi: 10.1016/j.jaad.2017.10.007. PMID: 29331386Free PMC Article
Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment.
Marur S, Forastiere AA
Mayo Clin Proc 2016 Mar;91(3):386-96. doi: 10.1016/j.mayocp.2015.12.017. PMID: 26944243

Recent clinical studies

Etiology

Chemoradiotherapy vs radiotherapy for non-surgical locally advanced laryngeal squamous cell carcinoma patients: a propensity score-matched study and practical nomogram construction.
Zhang Y, Wang Z, Zheng Y
Eur Arch Otorhinolaryngol 2024 Mar;281(3):1449-1456. Epub 2023 Dec 29 doi: 10.1007/s00405-023-08360-8. PMID: 38158418
A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
Incidence of thyroid gland invasion in advanced laryngeal cancers and its impact on disease-specific survival; a retrospective review at a tertiary care center.
Muhammad T, Dhanani R, Mohtasham S, Hussain M, Faisal M, Malik KI, Jamshed A, Hussain R
Acta Otolaryngol 2020 Oct;140(10):882-885. Epub 2020 Jul 7 doi: 10.1080/00016489.2020.1778786. PMID: 32633590
Could excision repair cross-complementing group-1 mRNA expression from peripheral blood lymphocytes predict locoregional failure with cisplatin chemoradiation for locally advanced laryngeal cancer?
Raturi VP, Wu CT, Mohammad S, Hojo H, Bei Y, Nakamura M, Okumura M, Rachi T, Singh R, Gupta R, Parmar D, Hasan F, Gaur J, Kishan D, Kumar S, Badajena A, Katepogu P, Shigematsu N
Asia Pac J Clin Oncol 2020 Apr;16(2):e19-e26. Epub 2019 Oct 15 doi: 10.1111/ajco.13239. PMID: 31612639
Prognostic significance of p16INK4a alterations and 9p21 loss of heterozygosity in locally advanced laryngeal squamous cell carcinoma.
Bazan V, Zanna I, Migliavacca M, Sanz-Casla MT, Maestro ML, Corsale S, Macaluso M, Dardanoni G, Restivo S, Quintela PL, Bernaldez R, Salerno S, Morello V, Tomasino RM, Gebbia N, Russo A
J Cell Physiol 2002 Sep;192(3):286-93. doi: 10.1002/jcp.10138. PMID: 12124774

Diagnosis

A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
Safety of combination treatment with imatinib mesylate, carboplatin, and cetuximab in a patient with multiple cancers: a case report.
Pala L, Bergamini C, Imbimbo M, Granata R, Locati L, Alfieri S, Licitra L, Bossi P
Tumori 2016 Nov 11;102(Suppl. 2) doi: 10.5301/tj.5000485. PMID: 26979243
TP53 mutations and S-phase fraction but not DNA-ploidy are independent prognostic indicators in laryngeal squamous cell carcinoma.
Russo A, Corsale S, Agnese V, Macaluso M, Cascio S, Bruno L, Surmacz E, Dardanoni G, Valerio MR, Vieni S, Restivo S, Fulfaro F, Tomasino RM, Gebbia N, Bazan V
J Cell Physiol 2006 Jan;206(1):181-8. doi: 10.1002/jcp.20447. PMID: 15965904

Therapy

A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
Could excision repair cross-complementing group-1 mRNA expression from peripheral blood lymphocytes predict locoregional failure with cisplatin chemoradiation for locally advanced laryngeal cancer?
Raturi VP, Wu CT, Mohammad S, Hojo H, Bei Y, Nakamura M, Okumura M, Rachi T, Singh R, Gupta R, Parmar D, Hasan F, Gaur J, Kishan D, Kumar S, Badajena A, Katepogu P, Shigematsu N
Asia Pac J Clin Oncol 2020 Apr;16(2):e19-e26. Epub 2019 Oct 15 doi: 10.1111/ajco.13239. PMID: 31612639
Safety of combination treatment with imatinib mesylate, carboplatin, and cetuximab in a patient with multiple cancers: a case report.
Pala L, Bergamini C, Imbimbo M, Granata R, Locati L, Alfieri S, Licitra L, Bossi P
Tumori 2016 Nov 11;102(Suppl. 2) doi: 10.5301/tj.5000485. PMID: 26979243

Prognosis

Chemoradiotherapy vs radiotherapy for non-surgical locally advanced laryngeal squamous cell carcinoma patients: a propensity score-matched study and practical nomogram construction.
Zhang Y, Wang Z, Zheng Y
Eur Arch Otorhinolaryngol 2024 Mar;281(3):1449-1456. Epub 2023 Dec 29 doi: 10.1007/s00405-023-08360-8. PMID: 38158418
A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
Incidence of thyroid gland invasion in advanced laryngeal cancers and its impact on disease-specific survival; a retrospective review at a tertiary care center.
Muhammad T, Dhanani R, Mohtasham S, Hussain M, Faisal M, Malik KI, Jamshed A, Hussain R
Acta Otolaryngol 2020 Oct;140(10):882-885. Epub 2020 Jul 7 doi: 10.1080/00016489.2020.1778786. PMID: 32633590
Functional organ preservation in locally advanced laryngeal squamous cell carcinoma: is there a role for induction chemotherapy?
Loo SW, Geropantas K, Roques TW
Clin Oncol (R Coll Radiol) 2013 May;25(5):298-307. Epub 2013 Jan 3 doi: 10.1016/j.clon.2012.12.001. PMID: 23290343
Prognostic significance of p16INK4a alterations and 9p21 loss of heterozygosity in locally advanced laryngeal squamous cell carcinoma.
Bazan V, Zanna I, Migliavacca M, Sanz-Casla MT, Maestro ML, Corsale S, Macaluso M, Dardanoni G, Restivo S, Quintela PL, Bernaldez R, Salerno S, Morello V, Tomasino RM, Gebbia N, Russo A
J Cell Physiol 2002 Sep;192(3):286-93. doi: 10.1002/jcp.10138. PMID: 12124774

Clinical prediction guides

Chemoradiotherapy vs radiotherapy for non-surgical locally advanced laryngeal squamous cell carcinoma patients: a propensity score-matched study and practical nomogram construction.
Zhang Y, Wang Z, Zheng Y
Eur Arch Otorhinolaryngol 2024 Mar;281(3):1449-1456. Epub 2023 Dec 29 doi: 10.1007/s00405-023-08360-8. PMID: 38158418
A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
Could excision repair cross-complementing group-1 mRNA expression from peripheral blood lymphocytes predict locoregional failure with cisplatin chemoradiation for locally advanced laryngeal cancer?
Raturi VP, Wu CT, Mohammad S, Hojo H, Bei Y, Nakamura M, Okumura M, Rachi T, Singh R, Gupta R, Parmar D, Hasan F, Gaur J, Kishan D, Kumar S, Badajena A, Katepogu P, Shigematsu N
Asia Pac J Clin Oncol 2020 Apr;16(2):e19-e26. Epub 2019 Oct 15 doi: 10.1111/ajco.13239. PMID: 31612639
Functional organ preservation in locally advanced laryngeal squamous cell carcinoma: is there a role for induction chemotherapy?
Loo SW, Geropantas K, Roques TW
Clin Oncol (R Coll Radiol) 2013 May;25(5):298-307. Epub 2013 Jan 3 doi: 10.1016/j.clon.2012.12.001. PMID: 23290343
Differential expression levels of urokinase-type plasminogen activator and cathepsin D in locally advanced laryngeal squamous cell carcinoma: clinical implications.
Leto G, Tumminello FM, Gebbia N, Bazan V, Tomasino RM, Dardanoni G, Russo A
Int J Biol Markers 2001 Oct-Dec;16(4):245-9. doi: 10.1177/172460080101600404. PMID: 11820719

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