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Advanced Laryngeal Squamous Cell Carcinoma

MedGen UID:
1665175
•Concept ID:
C4727687
•
Neoplastic Process
Synonym: Advanced Squamous Cell Carcinoma of the Larynx

Definition

A squamous cell carcinoma of the larynx that has spread extensively to other anatomic sites or is no longer responding to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAdvanced Laryngeal Squamous Cell Carcinoma

Professional guidelines

PubMed

Comparison of treatment modalities for selected advanced laryngeal squamous cell carcinoma.
Wushouer A, Li W, Zhang M, Lei D, Pan X
Eur Arch Otorhinolaryngol 2022 Jan;279(1):361-371. Epub 2021 Apr 17 doi: 10.1007/s00405-021-06780-y. PMID: 33864482
Chemoradiotherapy vs. total laryngectomy for primary treatment of advanced laryngeal squamous cell carcinoma.
Strojan P, Haigentz M Jr, Bradford CR, Wolf GT, Hartl DM, Langendijk JA, Rinaldo A, Eisbruch A, Mendenhall WM, Forastiere AA, Takes RP, Ferlito A
Oral Oncol 2013 Apr;49(4):283-6. Epub 2012 Dec 7 doi: 10.1016/j.oraloncology.2012.11.002. PMID: 23219843
Neoadjuvant therapy in cancer treatment.
Trimble EL, Ungerleider RS, Abrams JA, Kaplan RS, Feigal EG, Smith MA, Carter CL, Friedman MA
Cancer 1993 Dec 1;72(11 Suppl):3515-24. doi: 10.1002/1097-0142(19931201)72:11+<3515::aid-cncr2820721619>3.0.co;2-a. PMID: 8242583

Recent clinical studies

Etiology

Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models.
Zhang YF, Shen YJ, Huang Q, Wu CP, Zhou L, Ren HL
Sci Rep 2023 Oct 28;13(1):18498. doi: 10.1038/s41598-023-45831-8. PMID: 37898687Free PMC Article
A preliminary analysis of prognostic genes in advanced laryngeal squamous cell carcinoma patients with postoperative radiotherapy.
Hu C, Lao Z, Yan L, Song X, Wang J
Pathol Res Pract 2023 Jan;241:154229. Epub 2022 Nov 29 doi: 10.1016/j.prp.2022.154229. PMID: 36509010
Risk Factors for Functional Outcomes in Advanced Laryngeal Squamous Cell Carcinoma.
Lee DS, Lee JJ, Sinha P, Puram SV, Jackson RS, Adkins DR, Oppelt P, Brenneman R, Thorstad WL, Pipkorn P
Laryngoscope 2023 Mar;133(3):594-600. Epub 2022 May 25 doi: 10.1002/lary.30166. PMID: 35611799Free PMC Article
Comparison of treatment modalities for selected advanced laryngeal squamous cell carcinoma.
Wushouer A, Li W, Zhang M, Lei D, Pan X
Eur Arch Otorhinolaryngol 2022 Jan;279(1):361-371. Epub 2021 Apr 17 doi: 10.1007/s00405-021-06780-y. PMID: 33864482
The incidence of thyroid gland invasion in advanced laryngeal squamous cell carcinoma.
Al-Hakami HA, Al Garni MA, AlSubayea H, AlOtaibi Y, Neazy A, Jameel W, Albouq M, Alnufaie A, Fatani N
Braz J Otorhinolaryngol 2021 Sep-Oct;87(5):533-537. Epub 2019 Dec 9 doi: 10.1016/j.bjorl.2019.11.003. PMID: 31879196Free PMC Article

Diagnosis

Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models.
Zhang YF, Shen YJ, Huang Q, Wu CP, Zhou L, Ren HL
Sci Rep 2023 Oct 28;13(1):18498. doi: 10.1038/s41598-023-45831-8. PMID: 37898687Free PMC Article
A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
Nuclear HER3 expression improves the prognostic stratification of patients with HER1 positive advanced laryngeal squamous cell carcinoma.
Almadori G, Coli A, De Corso E, Mele DA, Settimi S, Di Cintio G, Brigato F, Scannone D, Carey TE, Paludetti G, Lauriola L, Ranelletti FO
J Transl Med 2021 Sep 27;19(1):408. doi: 10.1186/s12967-021-03081-0. PMID: 34579737Free PMC Article
A pilot study reveals the potential of miR-31-3p and miR-196a-5p as non-invasive biomarkers in advanced laryngeal cancer.
Kyurkchiyan SG, Popov TM, Shakola F, Rangachev J, Mitev VI, Kaneva R
Folia Med (Plovdiv) 2021 Jun 30;63(3):355-364. doi: 10.3897/folmed.63.e55346. PMID: 34196150
Risk of Recurrence in Laryngeal Cancer.
Brandstorp-Boesen J, Sørum Falk R, Folkvard Evensen J, Boysen M, Brøndbo K
PLoS One 2016;11(10):e0164068. Epub 2016 Oct 7 doi: 10.1371/journal.pone.0164068. PMID: 27716797Free PMC Article

Therapy

Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models.
Zhang YF, Shen YJ, Huang Q, Wu CP, Zhou L, Ren HL
Sci Rep 2023 Oct 28;13(1):18498. doi: 10.1038/s41598-023-45831-8. PMID: 37898687Free PMC Article
A Study of Peripheral Blood Parameters to Predict Response to Induction Chemotherapy and Overall Survival in Advanced Laryngeal Squamous Cell Carcinoma.
Xu J, Yang Y, Zhong Q, Hou L, Ma H, Zhang Y, Feng L, He S, Lian M, Fang J, Wang R
Curr Oncol 2022 Sep 9;29(9):6472-6484. doi: 10.3390/curroncol29090509. PMID: 36135078Free PMC Article
From VA Larynx to the future of chemoselection: Defining the role of induction chemotherapy in larynx cancer.
Spector ME, Rosko AJ, Swiecicki PL, Chad Brenner J, Birkeland AC
Oral Oncol 2018 Nov;86:200-205. Epub 2018 Oct 1 doi: 10.1016/j.oraloncology.2018.09.026. PMID: 30409302
Chemoradiotherapy vs. total laryngectomy for primary treatment of advanced laryngeal squamous cell carcinoma.
Strojan P, Haigentz M Jr, Bradford CR, Wolf GT, Hartl DM, Langendijk JA, Rinaldo A, Eisbruch A, Mendenhall WM, Forastiere AA, Takes RP, Ferlito A
Oral Oncol 2013 Apr;49(4):283-6. Epub 2012 Dec 7 doi: 10.1016/j.oraloncology.2012.11.002. PMID: 23219843
Neoadjuvant therapy in cancer treatment.
Trimble EL, Ungerleider RS, Abrams JA, Kaplan RS, Feigal EG, Smith MA, Carter CL, Friedman MA
Cancer 1993 Dec 1;72(11 Suppl):3515-24. doi: 10.1002/1097-0142(19931201)72:11+<3515::aid-cncr2820721619>3.0.co;2-a. PMID: 8242583

Prognosis

Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models.
Zhang YF, Shen YJ, Huang Q, Wu CP, Zhou L, Ren HL
Sci Rep 2023 Oct 28;13(1):18498. doi: 10.1038/s41598-023-45831-8. PMID: 37898687Free PMC Article
Risk Factors for Functional Outcomes in Advanced Laryngeal Squamous Cell Carcinoma.
Lee DS, Lee JJ, Sinha P, Puram SV, Jackson RS, Adkins DR, Oppelt P, Brenneman R, Thorstad WL, Pipkorn P
Laryngoscope 2023 Mar;133(3):594-600. Epub 2022 May 25 doi: 10.1002/lary.30166. PMID: 35611799Free PMC Article
Circular RNA MTCL1 promotes advanced laryngeal squamous cell carcinoma progression by inhibiting C1QBP ubiquitin degradation and mediating beta-catenin activation.
Wang Z, Sun A, Yan A, Yao J, Huang H, Gao Z, Han T, Gu J, Li N, Wu H, Li K
Mol Cancer 2022 Apr 2;21(1):92. doi: 10.1186/s12943-022-01570-4. PMID: 35366893Free PMC Article
Comparison of treatment modalities for selected advanced laryngeal squamous cell carcinoma.
Wushouer A, Li W, Zhang M, Lei D, Pan X
Eur Arch Otorhinolaryngol 2022 Jan;279(1):361-371. Epub 2021 Apr 17 doi: 10.1007/s00405-021-06780-y. PMID: 33864482
The incidence of thyroid gland invasion in advanced laryngeal squamous cell carcinoma.
Al-Hakami HA, Al Garni MA, AlSubayea H, AlOtaibi Y, Neazy A, Jameel W, Albouq M, Alnufaie A, Fatani N
Braz J Otorhinolaryngol 2021 Sep-Oct;87(5):533-537. Epub 2019 Dec 9 doi: 10.1016/j.bjorl.2019.11.003. PMID: 31879196Free PMC Article

Clinical prediction guides

Predicting survival of advanced laryngeal squamous cell carcinoma: comparison of machine learning models and Cox regression models.
Zhang YF, Shen YJ, Huang Q, Wu CP, Zhou L, Ren HL
Sci Rep 2023 Oct 28;13(1):18498. doi: 10.1038/s41598-023-45831-8. PMID: 37898687Free PMC Article
Risk Factors for Functional Outcomes in Advanced Laryngeal Squamous Cell Carcinoma.
Lee DS, Lee JJ, Sinha P, Puram SV, Jackson RS, Adkins DR, Oppelt P, Brenneman R, Thorstad WL, Pipkorn P
Laryngoscope 2023 Mar;133(3):594-600. Epub 2022 May 25 doi: 10.1002/lary.30166. PMID: 35611799Free PMC Article
Circular RNA MTCL1 promotes advanced laryngeal squamous cell carcinoma progression by inhibiting C1QBP ubiquitin degradation and mediating beta-catenin activation.
Wang Z, Sun A, Yan A, Yao J, Huang H, Gao Z, Han T, Gu J, Li N, Wu H, Li K
Mol Cancer 2022 Apr 2;21(1):92. doi: 10.1186/s12943-022-01570-4. PMID: 35366893Free PMC Article
Comparison of treatment modalities for selected advanced laryngeal squamous cell carcinoma.
Wushouer A, Li W, Zhang M, Lei D, Pan X
Eur Arch Otorhinolaryngol 2022 Jan;279(1):361-371. Epub 2021 Apr 17 doi: 10.1007/s00405-021-06780-y. PMID: 33864482
The incidence of thyroid gland invasion in advanced laryngeal squamous cell carcinoma.
Al-Hakami HA, Al Garni MA, AlSubayea H, AlOtaibi Y, Neazy A, Jameel W, Albouq M, Alnufaie A, Fatani N
Braz J Otorhinolaryngol 2021 Sep-Oct;87(5):533-537. Epub 2019 Dec 9 doi: 10.1016/j.bjorl.2019.11.003. PMID: 31879196Free PMC Article

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