U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lichenoid skin lesion

MedGen UID:
1627159
•Concept ID:
C4531107
•
Anatomical Abnormality
HPO: HP:0031452

Definition

Mutliple skin lesions resembling those characteristic of the disease lichen planus. These lesions are violaceous (reddish-purple), shiny, isolated, flat-topped papules and plaques. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLichenoid skin lesion

Professional guidelines

PubMed

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management [Formula: see text].
Muntyanu A, Netchiporouk E, Gerstein W, Gniadecki R, Litvinov IV
J Cutan Med Surg 2021 Jan-Feb;25(1):59-76. Epub 2020 Aug 3 doi: 10.1177/1203475420943260. PMID: 32746624
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241

Recent clinical studies

Etiology

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics.
Yew YW, Thyssen JP, Silverberg JI
J Am Acad Dermatol 2019 Feb;80(2):390-401. Epub 2018 Oct 1 doi: 10.1016/j.jaad.2018.09.035. PMID: 30287309
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Granulomatous & histiocytic dermatitides.
Wick MR
Semin Diagn Pathol 2017 May;34(3):301-311. Epub 2016 Dec 14 doi: 10.1053/j.semdp.2016.12.003. PMID: 28094163
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
Gorouhi F, Davari P, Fazel N
ScientificWorldJournal 2014;2014:742826. Epub 2014 Jan 30 doi: 10.1155/2014/742826. PMID: 24672362Free PMC Article

Diagnosis

Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Oral lichen planus: a literature review and update.
Alrashdan MS, Cirillo N, McCullough M
Arch Dermatol Res 2016 Oct;308(8):539-51. Epub 2016 Jun 27 doi: 10.1007/s00403-016-1667-2. PMID: 27349424
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
Gorouhi F, Davari P, Fazel N
ScientificWorldJournal 2014;2014:742826. Epub 2014 Jan 30 doi: 10.1155/2014/742826. PMID: 24672362Free PMC Article

Therapy

Adverse cutaneous toxicities by PD-1/PD-L1 immune checkpoint inhibitors: pathogenesis, treatment, and surveillance.
Bhardwaj M, Chiu MN, Pilkhwal Sah S
Cutan Ocul Toxicol 2022 Mar;41(1):73-90. Epub 2022 Feb 20 doi: 10.1080/15569527.2022.2034842. PMID: 35107396
Cutaneous Immune-Related Adverse Events (irAEs) to Immune Checkpoint Inhibitors: A Dermatology Perspective on Management [Formula: see text].
Muntyanu A, Netchiporouk E, Gerstein W, Gniadecki R, Litvinov IV
J Cutan Med Surg 2021 Jan-Feb;25(1):59-76. Epub 2020 Aug 3 doi: 10.1177/1203475420943260. PMID: 32746624
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113

Prognosis

A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics.
Yew YW, Thyssen JP, Silverberg JI
J Am Acad Dermatol 2019 Feb;80(2):390-401. Epub 2018 Oct 1 doi: 10.1016/j.jaad.2018.09.035. PMID: 30287309
Pityriasis Rosea: Diagnosis and Treatment.
Villalon-Gomez JM
Am Fam Physician 2018 Jan 1;97(1):38-44. PMID: 29365241
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Cutaneous and mucosal lichen planus: a comprehensive review of clinical subtypes, risk factors, diagnosis, and prognosis.
Gorouhi F, Davari P, Fazel N
ScientificWorldJournal 2014;2014:742826. Epub 2014 Jan 30 doi: 10.1155/2014/742826. PMID: 24672362Free PMC Article
Mucha-Habermann disease.
Bica BE, de Barros Mda G, Spingola C Jr
Rev Bras Reumatol 2013 May-Jun;53(3):314-7. doi: 10.1590/s0482-50042013000300011. PMID: 24051916

Clinical prediction guides

Diagnostic histochemistry in non-neoplastic skin diseases.
Wick MR, Patterson JW
Semin Diagn Pathol 2018 Nov;35(6):390-398. Epub 2018 Oct 16 doi: 10.1053/j.semdp.2018.10.006. PMID: 30509350
Toxic Side Effects of Targeted Therapies and Immunotherapies Affecting the Skin, Oral Mucosa, Hair, and Nails.
Lacouture M, Sibaud V
Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39. doi: 10.1007/s40257-018-0384-3. PMID: 30374901Free PMC Article
Dermatologic Reactions to Immune Checkpoint Inhibitors : Skin Toxicities and Immunotherapy.
Sibaud V
Am J Clin Dermatol 2018 Jun;19(3):345-361. doi: 10.1007/s40257-017-0336-3. PMID: 29256113
Dermatoscopy in inflammatory and infectious skin disorders.
Lacarrubba F, Verzì AE, Dinotta F, Scavo S, Micali G
G Ital Dermatol Venereol 2015 Oct;150(5):521-31. PMID: 26333553
Delayed cutaneous manifestations of drug hypersensitivity.
Bircher AJ, Scherer K
Med Clin North Am 2010 Jul;94(4):711-25, x. doi: 10.1016/j.mcna.2010.04.001. PMID: 20609859

Recent systematic reviews

Lichen planus pemphigoides with predominant mucous membrane involvement: a series of 12 patients and a literature review.
Combemale L, Bohelay G, Sitbon IY, Ahouach B, Alexandre M, Martin A, Pascal F, Soued I, Doan S, Morin F, Grootenboer-Mignot S, Caux F, Prost-Squarcioni C, Le Roux-Villet C
Front Immunol 2024;15:1243566. Epub 2024 Apr 15 doi: 10.3389/fimmu.2024.1243566. PMID: 38686381Free PMC Article
A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics.
Yew YW, Thyssen JP, Silverberg JI
J Am Acad Dermatol 2019 Feb;80(2):390-401. Epub 2018 Oct 1 doi: 10.1016/j.jaad.2018.09.035. PMID: 30287309
Lymphomatoid Papulosis in Children and Adolescents: A Systematic Review.
Wieser I, Wohlmuth C, Nunez CA, Duvic M
Am J Clin Dermatol 2016 Aug;17(4):319-27. doi: 10.1007/s40257-016-0192-6. PMID: 27138554
Urban legends series: lichen planus.
Baccaglini L, Thongprasom K, Carrozzo M, Bigby M
Oral Dis 2013 Mar;19(2):128-43. Epub 2012 Jul 13 doi: 10.1111/j.1601-0825.2012.01953.x. PMID: 22788669
Chronic ulcerative stomatitis: diagnostic and management challenges--four new cases and review of literature.
Islam MN, Cohen DM, Ojha J, Stewart CM, Katz J, Bhattacharyya I
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 Aug;104(2):194-203. Epub 2007 Jun 7 doi: 10.1016/j.tripleo.2007.02.013. PMID: 17560144

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...