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Status |
Public on Jun 30, 2016 |
Title |
Microarray analysis of liver and mammary gland biopsies of dairy cows supplemented with vitamins B9 and B12 alone or in combination |
Organism |
Bos taurus |
Experiment type |
Expression profiling by array
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Summary |
Data from one animal from B9_B12 group (Cow 31) were not taken into account for the liver samples Treated animals were compared to control (non supplemented cows)
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Overall design |
Twenty four multiparous Holstein cows were assigned to 6 blocks of 4 animals according to their 305-d milk production during the previous lactation to one of the following treatments: injections saline 0.9% NaCl (Ctl); folic acid (B9); vitamin B12 (B12) or folic acid and vitamin B12 (B9_B12). Biopsies of hepatic (foie for liver) and mammary (mam for mammary gland) tissues were taken from these 24 cows. Microarray analyses were performed on samples from both tissues for 3 animals per treatment in CTL, B9 and B9_B12 and for 4 animals in B12 treatment. Data for hepatic tissue of animal 31 (group B9_B12) were not included. For both tissues, treated animals were compared to control.
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Contributor(s) |
Bissonnette N, Ouattara B, Duplessis M, Girard CL |
Citation(s) |
27526683 |
Submission date |
Jan 29, 2016 |
Last update date |
Sep 29, 2016 |
Contact name |
Bazoumana Ouattara |
Phone |
819 565 9171
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Organization name |
Sherbrooke Research and Development Centre
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Department |
Agriculture and Agri-Food Canada
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Lab |
Lennoxville
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Street address |
2000 College
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City |
Sherbrooke |
State/province |
Quebec |
ZIP/Postal code |
J1M 0C8 |
Country |
Canada |
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Platforms (1) |
GPL11648 |
Agilent-023647 B. taurus (Bovine) Oligo Microarray v2 (Feature Number version) |
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Samples (25)
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Relations |
BioProject |
PRJNA310249 |