|
| Status |
Public on Feb 22, 2018 |
| Title |
The signature of liver cancer in host peripheral blood mononuclear cells and T cells DNA methylation |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
We demonstrate the feasibility of developing noninvasive DNA methylation biomarkers of early stages of HCC in the host T cells. These data are consistent with involvement of epigenetic modulation of the immune system in HCC.
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| |
|
| Overall design |
Examination of DNA methylation signatures in peripheral blood mononuclear cells and T cells from liver cancer (stage 1-4), Hepatitis and control patients
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| |
|
| Contributor(s) |
Zhang Y, Petropoulos S, Jinhua L, Dymov S, Li N, Szyf M |
| Citation(s) |
29375724 |
| Submission date |
Mar 23, 2015 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Moshe Szyf |
| Organization name |
McGill University
|
| Street address |
3655 Sir William Osler Promenade
|
| City |
Montreal |
| ZIP/Postal code |
H3G 1Y6 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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| Samples (89)
|
|
| Relations |
| BioProject |
PRJNA279155 |
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