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Series GSE18560 Query DataSets for GSE18560
Status Public on Nov 29, 2011
Title Deciphering the Wnt-dependent gene signature in colorectal cancer cells
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Microarray-based gene expression data were generated from RNA from Ls174T colorectal carcinoma cell lines in which Wnt-dependent transcriptional activity can be abrogated by inducible overexpression of a dominant-negative form of Tcf4 or siRNA against β-catenin.
 
Overall design shRNA against β-catenin, or a dominant-negative Tcf4 transgene, were induced in Ls174T cells for 72 or 24 hours, respectively. Uninduced cells were used as a control. Three replicates per condition.
 
Contributor(s) Mokry M, Hatzis P, de Bruijn E, Koster J, Versteeg R, van de Wetering M, Guryev V, Clevers H, Cuppen E
Citation(s) 21914722
Submission date Oct 14, 2009
Last update date Mar 25, 2019
Contact name Linda Valentijn
Organization name Academic Medical Centre, University of Amsterdam
Department Department of Oncogenomics
Street address P.O. Box 22700
City Amsterdam
ZIP/Postal code 1100DE
Country Netherlands
 
Platforms (1)
GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array
Samples (12)
GSM461942 Ls174T-pTER-β-catenin con1
GSM461943 Ls174T-L8 dox2
GSM461944 Ls174T-L8 con3
Relations
BioProject PRJNA121379

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE18560_RAW.tar 47.8 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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