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    VTRNA1-2 vault RNA 1-2 [ Homo sapiens (human) ]

    Gene ID: 56663, updated on 10-Oct-2023

    Summary

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    Official Symbol
    VTRNA1-2provided by HGNC
    Official Full Name
    vault RNA 1-2provided by HGNC
    Primary source
    HGNC:HGNC:12655
    See related
    Ensembl:ENSG00000202111 MIM:612696; AllianceGenome:HGNC:12655
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    VR2; HVG2; hvg-2; VAULTRC2
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    Genomic context

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    Location:
    5q31.3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (140718926..140719013)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (141244309..141244396)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (140098511..140098598)

    Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23288 Neighboring gene NANOG hESC enhancer GRCh37_chr5:140082322-140082864 Neighboring gene zinc finger matrin-type 2 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr5:140090124-140091323 Neighboring gene uncharacterized LOC105378198 Neighboring gene vault RNA 1-1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 23290 Neighboring gene Sharpr-MPRA regulatory region 6103 Neighboring gene vault RNA 1-3 Neighboring gene ZFP14 zinc finger protein pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Vaults are up-regulated in multidrug-resistant cancer cell lines. Kickhoefer VA, et al. J Biol Chem, 1998 Apr 10. PMID 9535882
    2. Epstein-barr virus-induced expression of a novel human vault RNA. Nandy C, et al. J Mol Biol, 2009 May 15. PMID 19298825
    3. Evolution of vault RNAs. Stadler PF, et al. Mol Biol Evol, 2009 Sep. PMID 19491402
    4. Vaults and telomerase share a common subunit, TEP1. Kickhoefer VA, et al. J Biol Chem, 1999 Nov 12. PMID 10551828
    5. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. Warnatz HJ, et al. J Biol Chem, 2011 Jul 1. PMID 21555518, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. VTRNA1-2 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.
      Title: The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
    Submit: New GeneRIF Correction

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Genotypes

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • vault RNA component 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_026704.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AF045144
      Related
      ENST00000365241.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

      Range
      140718926..140719013
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060929.1 Alternate T2T-CHM13v2.0

      Range
      141244309..141244396
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

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    Molecular Biology Databases