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    Nlrp14 NLR family pyrin domain containing 14 [ Fukomys damarensis (Damara mole-rat) ]

    Gene ID: 104856513, updated on 12-Mar-2024

    Summary

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    Gene symbol
    Nlrp14
    Gene description
    NLR family pyrin domain containing 14
    Locus tag
    H920_20215
    See related
    Ensembl:ENSFDAG00000007245
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Fukomys damarensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
    Orthologs
    human mouse all
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    Genomic context

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    See Nlrp14 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900928.1 (22043368..22092333, complement)
    101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011048031.1 (343784..371385)

    NW_022900928.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin 9 Neighboring gene RNA-binding motif protein, X chromosome Neighboring gene uncharacterized LOC104856537 Neighboring gene olfactory receptor 2D3 Neighboring gene zinc finger protein 215

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    NACHT, LRR and PYD domains-containing protein 14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference DMR_v1.0_HiC Primary Assembly

    Genomic

    1. NW_022900928.1 Reference DMR_v1.0_HiC Primary Assembly

      Range
      22043368..22092333 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_033764173.1 → XP_033620064.1  NACHT, LRR and PYD domains-containing protein 14 isoform X3

      Conserved Domains (5) summary
      sd00033
      Location:629 → 657
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:74 → 247
      NACHT; NACHT domain
      pfam17776
      Location:382 → 499
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:325 → 380
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:658 → 954
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    2. XM_033764172.1 → XP_033620063.1  NACHT, LRR and PYD domains-containing protein 14 isoform X3

      Conserved Domains (5) summary
      sd00033
      Location:629 → 657
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:74 → 247
      NACHT; NACHT domain
      pfam17776
      Location:382 → 499
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:325 → 380
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:658 → 954
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    3. XM_033764170.1 → XP_033620061.1  NACHT, LRR and PYD domains-containing protein 14 isoform X1

      UniProtKB/TrEMBL
      A0A091CIV5
      Conserved Domains (6) summary
      cd08320
      Location:29 → 94
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:729 → 757
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:174 → 347
      NACHT; NACHT domain
      pfam17776
      Location:482 → 599
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:425 → 480
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:758 → 1054
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    4. XM_033764171.1 → XP_033620062.1  NACHT, LRR and PYD domains-containing protein 14 isoform X2

      Conserved Domains (5) summary
      sd00033
      Location:719 → 747
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:164 → 337
      NACHT; NACHT domain
      pfam17776
      Location:472 → 589
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:415 → 470
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:748 → 1044
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

    5. XM_010615942.1 → XP_010614244.1  NACHT, LRR and PYD domains-containing protein 14 isoform X1

      See identical proteins and their annotated locations for XP_010614244.1

      UniProtKB/TrEMBL
      A0A091CIV5
      Related
      ENSFDAP00000022072.1, ENSFDAT00000010443.1
      Conserved Domains (6) summary
      cd08320
      Location:29 → 94
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:729 → 757
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:174 → 347
      NACHT; NACHT domain
      pfam17776
      Location:482 → 599
      NLRC4_HD2; NLRC4 helical domain HD2
      pfam17779
      Location:425 → 480
      NOD2_WH; NOD2 winged helix domain
      cl39015
      Location:758 → 1054
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
    Nucleotide Protein
    Heading Accession and Version

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