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    Trem6l triggering receptor expressed on myeloid cells-like 6 [ Mus musculus (house mouse) ]

    Gene ID: 320148, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Trem6lprovided by MGI
    Official Full Name
    triggering receptor expressed on myeloid cells-like 6provided by MGI
    Primary source
    MGI:MGI:2443478
    See related
    Ensembl:ENSMUSG00000043740 AllianceGenome:MGI:2443478
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Treml6; B430306N03Rik
    Summary
    Predicted to enable signaling receptor activity. Predicted to be active in cell surface. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in spleen adult (RPKM 4.5), testis adult (RPKM 4.0) and 13 other tissues See more
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    Genomic context

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    Location:
    17 C; 17 23.99 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (48622310..48632580)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (48315279..48326511)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52308 Neighboring gene triggering receptor expressed on myeloid cells-like 4 Neighboring gene STARR-positive B cell enhancer ABC_E9957 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:48439578-48439845 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:48440299-48440452 Neighboring gene triggering receptor expressed on myeloid cells-like 2 Neighboring gene STARR-positive B cell enhancer ABC_E8680 Neighboring gene triggering receptor expressed on myeloid cells 2 Neighboring gene triggering receptor expressed on myeloid cells-like 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Double-stranded RNA analog and type I interferon regulate expression of Trem paired receptors in murine myeloid cells. Kasamatsu J, et al. BMC Immunol, 2016 May 3. PMID 27141827, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    trem-like transcript 6 protein
    Names
    triggering receptor expressed on myeloid cells-like 6b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418741.1 → NP_001405670.1  trem-like transcript 6 protein isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC166164

    2. NM_177083.5 → NP_796057.1  trem-like transcript 6 protein isoform 1 precursor

      See identical proteins and their annotated locations for NP_796057.1

      Status: VALIDATED

      Source sequence(s)
      AC166164
      Consensus CDS
      CCDS28864.1
      UniProtKB/TrEMBL
      Q6QX36
      Related
      ENSMUSP00000054890.7, ENSMUST00000049614.13
      Conserved Domains (2) summary
      cd05716
      Location:28 → 121
      Ig_pIgR; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR)
      smart00410
      Location:26 → 121
      IG_like; Immunoglobulin like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      48622310..48632580
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006524395.5 → XP_006524458.1  trem-like transcript 6 protein isoform X2

      Conserved Domains (1) summary
      cd05716
      Location:28 → 121
      Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains

    2. XM_006524394.5 → XP_006524457.1  trem-like transcript 6 protein isoform X1

      Conserved Domains (1) summary
      cd05716
      Location:28 → 121
      Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains
    Nucleotide Protein Strain
    Heading Accession and Version

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