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    scnn1g.S sodium channel, non voltage gated 1 gamma subunit S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 373668, updated on 6-Jun-2024

    Summary

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    Official Symbol
    scnn1g.S
    Official Full Name
    sodium channel, non voltage gated 1 gamma subunit S homeolog
    Primary source
    Xenbase:XB-GENE-6252871
    Locus tag
    XELAEV_18047658mg
    See related
    EnsemblRapid:ENSXLAG00005007967
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    pha1; enacg; scneg; scnn1g; scnn1g-a; scnn1g-b; ENaCgamma; gamma-ENaC; gamma XENaC; gamma2xENaC-A
    Annotation information
    Annotation category: partial on reference assembly
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    Genomic context

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    See scnn1g.S in Genome Data Viewer
    Location:
    chromosome: 9_10S
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (98906371..98921505)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (92263127..92278284)

    Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene heparan sulfate-glucosamine 3-sulfotransferase 2 S homeolog Neighboring gene ubiquitin specific peptidase 31 S homeolog Neighboring gene sodium channel, non voltage gated 1 beta subunit S homeolog Neighboring gene component of oligomeric golgi complex 7 S homeolog Neighboring gene glutamyl-tRNA synthetase 2, mitochondrial S homeolog

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Novel isoforms of the beta and gamma subunits of the Xenopus epithelial Na channel provide information about the amiloride binding site and extracellular sodium sensing. Puoti A, et al. Proc Natl Acad Sci U S A, 1997 May 27. PMID 9159181, Free PMC Article
    2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Plasmin in nephrotic urine activates the epithelial sodium channel
      Title: Plasmin in nephrotic urine activates the epithelial sodium channel.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Clone Names

    • MGC81424

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables ligand-gated sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transmembrane transport ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    amiloride-sensitive sodium channel subunit gamma-2
    Names
    SCNEG2
    epithelial Na(+) channel subunit gamma-2
    gamma-2-ENaC
    gamma-2-NaCH
    gamma2 subunit of epithelial sodium channel
    nonvoltage-gated sodium channel 1 subunit gamma-2
    sodium channel, non-voltage-gated 1, gamma subunit
    sodium channel, nonvoltage-gated 1, gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001085662.2 → NP_001079131.2  amiloride-sensitive sodium channel subunit gamma-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      JAGEVR010000039
      UniProtKB/Swiss-Prot
      O13263
      Related
      ENSXLAP00005022829.1, ENSXLAT00005023531.1

    2. NM_001096984.2 → NP_001090453.2  amiloride-sensitive sodium channel subunit gamma-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      JAGEVR010000039
      UniProtKB/Swiss-Prot
      O13263
      UniProtKB/TrEMBL
      A0A974BVP3

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      98906371..98921505
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O13263.1 GenPept UniProtKB/Swiss-Prot:O13263

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